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Related Concept Videos

Pain01:20

Pain

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Pain serves as a critical warning signal that alerts the body to potential or actual harm. When mechanical pressure on the skin is intense, such as from a sharp pinch, the sensation transitions from touch to pain. Similarly, extreme temperatures, like a hot pot handle, convert the sensation of heat into pain. Pain can also result from overstimulation of other senses, such as blinding light, loud noise, or the intense heat from habañero peppers. This ability to sense pain is essential for...
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Analgesia and Pain Management01:25

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Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
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Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...
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Pericarditis IV: Nursing Management01:25

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Pericarditis, an inflammation of the pericardium, necessitates diligent nursing management to ensure effective patient care and recovery. The initial step in managing pericarditis is a comprehensive patient medical assessment.The patient reports chest pain aggravated by breathing, coughing, and swallowing, which worsens when lying supine. The pain often improves when sitting up and leaning forward. Additional symptoms may include fever, malaise, and, in severe cases, signs of heart failure.
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Pneumonia II: Pathophysiology01:29

Pneumonia II: Pathophysiology

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The pathophysiology of pneumonia involves the following steps:
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Pleural Effusion II: Symptoms and Management01:28

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Pleural Effusion Overview
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
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Updated: Nov 17, 2025

Objective Nociceptive Assessment in Ventilated ICU Patients: A Feasibility Study Using Pupillometry and the Nociceptive Flexion Reflex
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Pain in Covid Era.

Heloísa Alonso-Matielo1, Victória Regina da Silva Oliveira1, Victhor Teixeira de Oliveira1

  • 1Department of Anatomy, Laboratory of Neuromodulation and Experimental Pain, University of São Paulo, São Paulo, Brazil.

Frontiers in Physiology
|February 19, 2021
PubMed
Summary

The COVID-19 pandemic causes significant pain, affecting survivors long after recovery. This review explores acute and chronic pain conditions linked to COVID-19 infection.

Keywords:
SARS-CoV-2acute painchronic paincomorbiditypandemic (COVID19)

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Area of Science:

  • Infectious Diseases
  • Neurology
  • Pain Management

Background:

  • COVID-19 primarily presents with respiratory symptoms, but affects multiple organ systems.
  • A significant percentage of patients develop severe disease requiring hospitalization.
  • Long-term sequelae, including pain, impact survivors' quality of life.

Purpose of the Study:

  • To review the implications of COVID-19 on acute and chronic pain.
  • To highlight the limited understanding of pain in COVID-19 survivors.
  • To provide an overview of clinical characteristics, treatment, and outcomes of COVID-19-related pain.

Main Methods:

  • Narrative review of existing literature.
  • Analysis of studies on COVID-19 and its impact on various physiological systems.
  • Synthesis of information regarding pain manifestations and management.

Main Results:

  • Pain is a common, yet poorly understood, symptom in COVID-19 patients.
  • Multisystemic involvement in COVID-19 can contribute to diverse pain conditions.
  • Cognitive, physical, and psychological dysfunctions are reported post-discharge, often including pain.

Conclusions:

  • COVID-19 has significant implications for both acute and chronic pain states.
  • Further research is needed to understand the mechanisms, treatment, and outcomes of pain in COVID-19 survivors.
  • Multidisciplinary interventions are crucial for managing post-COVID-19 sequelae, including pain.