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Risk factors for respiratory assistance in premature infants

Hai-Xin Li1, Cai-Jie Gao2, Shan Cheng2

  • 1Department of Child Healthcare, Changzhou Women and Children Health Care Hospital, Changzhou, Jiangsu 213000, P.R. China.

Experimental and Therapeutic Medicine
|February 19, 2021
PubMed

Insights

Premature infants often need respiratory assistance due to immature development. Key risk factors include placental abnormality, cesarean delivery, low Apgar scores, low birth weight, and low gestational age.

Area of Science:

  • Neonatal Medicine
  • Pediatric Respiratory Medicine

Background:

  • Premature infants frequently experience respiratory distress and require respiratory support due to developmental immaturity.
  • Identifying risk factors for respiratory assistance in this vulnerable population is crucial for timely intervention.

Purpose of the Study:

  • To retrospectively analyze independent risk factors associated with the need for respiratory assistance in premature infants.

Main Methods:

  • A retrospective analysis was conducted on a cohort of 3,394 premature infants.
  • Multivariate logistic regression was employed to identify independent risk factors for respiratory assistance.

Main Results:

  • Placental abnormality (OR=1.284), cesarean section delivery (OR=1.538), low 1-minute Apgar score (OR=0.727), low birth weight (OR=0.999), and low gestational age (OR=0.616) were identified as independent risk factors.
  • Male sex was found to be a protective factor (OR=0.696).

Conclusions:

  • Several factors at birth, including placental abnormalities, delivery method, Apgar score, birth weight, and gestational age, are significant predictors for respiratory assistance in premature infants.
  • Risk assessment at birth can guide timely respiratory support, potentially improving survival rates.

Keywords:
premature infantsrespiratory assistancerisk factors

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