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Updated: Aug 18, 2026
Induction of Intestinal Graft-versus-host Disease and Its Mini-endoscopic Assessment in Live Mice
Published on: February 11, 2019
[Preclinical results with 15-deoxyspergualin in experimental graft versus host disease]
G Dickneite1, H U Schorlemmer, H H Sedlacek
1Forschungslaboratorien der Behringwerke AG, Marburg.
Abstract:
The efficacy of 15-deoxyspergualin (15-DS) was tested in two models of experimental graft versus host disease (GvHD) in mice. In both models, which lead to a hemolytic anemia or to a glomerulonephritis respectively followed by subsequent death of the animals, 15-deoxyspergualin showed good therapeutic effects.
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