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E-PSMA: the EANM standardized reporting guidelines v1.0 for PSMA-PET.
Francesco Ceci1, Daniela E Oprea-Lager2, Louise Emmett3,4
1Nuclear Medicine, Department of Medical Sciences, University of Turin, Turin, Italy.
European Journal of Nuclear Medicine and Molecular Imaging
|February 19, 2021
Summary
Consensus guidelines for Prostate-Specific Membrane Antigen (PSMA)-Positron Emission Tomography (PET) interpretation are established. These E-PSMA guidelines standardize reporting for consistent clinical practice and reproducible clinical trials in prostate cancer.
Area of Science:
- Nuclear Medicine
- Radiology
- Oncology
Background:
- Prostate-Specific Membrane Antigen (PSMA)-Positron Emission Tomography (PET) is a crucial imaging modality in prostate cancer management.
- Lack of standardized interpretation guidelines leads to inconsistent reporting and reduced data reproducibility in clinical trials.
- Clear communication of PSMA-PET findings is essential for effective therapeutic decision-making.
Purpose of the Study:
- To develop consensus-based guidelines for the interpretation of PSMA-PET imaging.
- To establish standardized reporting criteria for PSMA-PET in prostate cancer.
- To harmonize diagnostic interpretation to improve consistency and reproducibility.
Main Methods:
- A modified, non-anonymous Delphi consensus process was employed.
- A worldwide panel of experts in PSMA-PET imaging was assembled.
- Panelists were selected based on expertise in prostate cancer diagnosis, treatment, and PSMA-PET applications.
Main Results:
- Panelist recommendations from the Delphi process were synthesized.
- A structured report format for PSMA-PET interpretation was developed.
- Consensus statements on diagnostic criteria were formulated.
Conclusions:
- The E-PSMA standardized reporting guidelines offer consensus statements for PSMA-PET interpretation.
- These guidelines, supported by the European Association of Nuclear Medicine (EANM), aim to harmonize diagnostic criteria.
- Implementation of these guidelines will enhance consistency in clinical practice and data reproducibility in research.
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