Related Experiment Video

Updated: Nov 16, 2025

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
07:54

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

20.2K

Incidence / predictors of pediatric obstructive sleep apnea with normal oximetry

Chonlada Chuanprasitkul1, Montida Veeravigrom2,3,4, Kanokkarn Sunkonkit5

  • 1Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

Pediatrics International : Official Journal of the Japan Pediatric Society
|February 19, 2021
PubMed

Insights

Obstructive sleep apnea (OSA) is highly prevalent in children with adenotonsillar hypertrophy (ATH) even with normal oximetry. Allergic rhinitis and arousal index predict pediatric OSA, aiding in diagnosis.

Area of Science:

  • Pediatric Pulmonology
  • Sleep Medicine
  • Otolaryngology

Background:

  • Polysomnography (PSG) is the gold standard for diagnosing obstructive sleep apnea (OSA).
  • Nocturnal oximetry serves as a practical screening tool for children with adenotonsillar hypertrophy (ATH).
  • This study addresses the incidence and predictors of OSA in children with ATH and normal/inconclusive oximetry results.

Purpose of the Study:

  • To determine the incidence of OSA in children aged 3-15 years with ATH and normal or inconclusive overnight oximetry.
  • To identify predictive factors for OSA in this specific pediatric population.
  • To evaluate the utility of clinical and polysomnographic parameters in predicting OSA severity.

Main Methods:

  • Prospective study including 189 children aged 3-15 years with ATH and normal/inconclusive oximetry.
  • All participants underwent full-night polysomnography (PSG).
  • Logistic regression analysis was used to assess predictors including history of allergic rhinitis, BMI z-score, neck circumference-height ratio, and PSG parameters (OAHI, nadir SpO2, peak end-tidal CO2, arousal index).

Main Results:

  • A high incidence of OSA was observed, with 167 (88%) children diagnosed via PSG.
  • Predictors for OSA diagnosis included a history of allergic rhinitis (P=0.033), nadir SpO2 (P=0.027), and arousal index (P<0.001).
  • Severe OSA (OAHI ≥10) was diagnosed in 31% of participants, with the arousal index being the sole significant predictor (P<0.001).

Conclusions:

  • Pediatric OSA is highly prevalent in children with ATH and normal/inconclusive oximetry.
  • A history of allergic rhinitis may assist in patient triage for further investigation.
  • The arousal index is a significant predictor of pediatric OSA, particularly severe cases.
Abstract

Keywords:
adenotonsillar hypertrophynocturnal oximetryobstructive sleep apnea

More Related Videos

Conducting Respiratory Oscillometry in an Outpatient Setting14:49

Conducting Respiratory Oscillometry in an Outpatient Setting

Published on: April 8, 2022

7.9K
A Model to Simulate Clinically Relevant Hypoxia in Humans09:54

A Model to Simulate Clinically Relevant Hypoxia in Humans

Published on: December 22, 2016

9.1K

Related Concept Videos

Sleep Apnea01:21

Sleep Apnea

Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
305
Respiratory Assessment: Purpose and Indications01:19

Respiratory Assessment: Purpose and Indications

Respiratory assessment is a cornerstone of nursing assessments, crucial for the early detection of patient deterioration. This evaluation transcends routine procedures, representing a critical skill nurses must master to ensure optimal patient care.
Objectives and Importance:
The primary goal of respiratory assessment is to evaluate patients at early risk of clinical deterioration. Since respiratory distress often precedes other signs of declining health, breathing patterns and sounds become a...
1.4K
Special considerations while measuring oxygen saturation01:19

Special considerations while measuring oxygen saturation

Assessing respiratory rate concurrently with pulse measurement is fundamental to patient care, providing valuable insights into the patient's respiratory function. The normal breathing rate for an adult usually falls within a normal range of 12 to 20 breaths per minute. Abnormal respiratory rates can signal underlying health conditions or the need for immediate intervention.
Ensuring accuracy in vital sign recordings while prioritizing patient comfort and minimizing anxiety is...
782
Pulse Oximetry01:24

Pulse Oximetry

Pulse oximetry, or SpO2, is a non-invasive method for continuously monitoring arterial oxygen saturation (SaO2). This procedure involves attaching a probe or sensor to the patient's fingertip, forehead, earlobe, or nose bridge. The sensor works by detecting changes in oxygen saturation levels through light signals generated by the oximeter and reflected by the pulsing blood under the probe.
Purpose
Average SpO2 values are greater than 95%. If the readings fall below 90%, it indicates that...
1.0K
Assessment of Airway, Skin Color, and Use of Accessory Muscles01:30

Assessment of Airway, Skin Color, and Use of Accessory Muscles

A thorough assessment of respiratory health is paramount in clinical settings to identify and manage respiratory distress and ensure adequate oxygenation. This article elaborates on the critical aspects of respiratory evaluation, including airway assessment, skin color examination, and the observation of accessory muscle use, which are integral to effectively diagnosing and managing patients with respiratory conditions.
Introduction
The initial evaluation of a patient's respiratory system...
1.3K
Respiratory Volumes and Capacities I01:26

Respiratory Volumes and Capacities I

Assessing the respiratory rate and rhythm for a complete minute is crucial for evaluating the breathing pattern. Even a minor increase in the patient's average respiratory rate, by as little as three to five breaths per minute, is an early and vital indicator of respiratory distress. Patients with a respiratory rate exceeding twenty-four breaths per minute require close monitoring to determine the physiological alterations. This careful observation is essential for prompt recognition and...
1.4K