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Heart Sound Analysis in Individuals Supported With Left Ventricular Assist Devices.
IEEE Transactions on Bio-Medical Engineering
|February 19, 2021
Summary
This study developed a signal processing method to reduce noise from mechanical heart pumps (LVADs). This allows for clearer analysis of heart sounds, aiding early detection of complications in patients with advanced heart failure.
Area of Science:
- Biomedical Engineering
- Cardiology
- Signal Processing
Background:
- Left Ventricular Assist Devices (LVADs) improve survival in advanced heart failure but are linked to high morbidity.
- Current monitoring relies on frequent clinical visits, posing challenges for early complication detection.
- LVAD-generated noise interferes with traditional cardiac auscultation.
Purpose of the Study:
- To develop a signal processing pipeline to mitigate LVAD sounds.
- To enable analysis of intrinsic heart sounds for improved patient monitoring.
- To explore real-time, remote monitoring for early detection of LVAD complications.
Main Methods:
- Collected in vivo precordial sounds from 17 LVAD recipients.
- Acquired contemporaneous echocardiograms from 12 recipients to validate heart valve timings.
- Developed and applied a signal processing pipeline to reduce LVAD acoustic interference.
Main Results:
- Characterized acoustic signatures of heart sounds from LVAD recipients.
- Identified preliminary links between heart sound characteristics and LVAD support levels.
- Successfully mitigated LVAD sounds, enabling intrinsic heart sound analysis.
Conclusions:
- LVAD sound mitigation allows for the analysis of intrinsic heart sounds.
- This approach provides proof-of-concept for bedside and remote monitoring of LVAD patients.
- Heart sound analysis shows potential for early detection of LVAD complications.
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