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Infections in Cirrhosis: A Guide for the Clinician
Kirsti A Campbell1, Hirsh D Trivedi1, Sanjiv Chopra1
1Beth Israel Deaconess Medical Center, Boston, Mass; Harvard Medical School, Boston, Mass.
Abstract:
Cirrhosis contributes significantly to morbidity and mortality worldwide. Infections in patients with cirrhosis are common and significantly impact health-related quality of life. As our understanding of immune dysfunction associated with cirrhosis grows and as rates of drug-resistant organisms increase, the management of infections in cirrhosis has become increasingly nuanced. In this review, we discuss the current understanding of cirrhosis-associated immune deficiency, review the most common infections in patients with cirrhosis, and highlight techniques for the general clinician in the prevention and treatment of infections in this high-risk population.
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