Molybdenum-containing polypyrrole self-supporting hollow flexible electrode for hydrogen peroxide detection in living...

A flexible electrode based on polypyrrole-supported free-standing molybdenum oxide-molybdenum disulfide/polypyrrole nanostructure (MoO₃-MoS₂/PPy) was synthesized. The petal-like MoO₃-MoS₂ sheets grown on PPy were prepared step by step through simple electrodeposition and hydrothermal methods. The corresponding surface morphological and structural characterizations were characterized by field emission scanning electron microscopy (FESEM), X-ray diffraction (XRD) and X-ray photoelectron spectroscopy (XPS). The results showed that the prepared petal MoO₃-MoS₂ hybrid nanomaterials were uniformly distributed on the PPy skeleton and exhibited a three-dimensional porous network structure. The flexible electrode was used for non-enzymatic detection of hydrogen peroxide (H₂O₂), and the developed MoO₃-MoS₂/PPy nanomaterials exhibited high electrochemical sensing performance in the range of 0.3-150 μM, with the detection limit of 0.18 μM (S/N = 3). The excellent detection properties enabled the MoO₃-MoS₂/PPy flexible electrode to detect H₂O₂ released by living cells. The resulting MoO₃-MoS₂/PPy flexible electrode also has the advantages of customizable shape and adjustability, which provides a potential platform for constructing clinically diagnosed in vivo portable instruments and real-time environmental monitoring.