Related Experiment Video
Updated: Nov 16, 2025

Establishment of a Minimally Invasive Rat Model of Pulmonary Embolism Using Autologous Blood Clots
Published on: October 25, 2024
Risk scoring models fail to predict pulmonary embolism in trauma patients
Frank R Buchanan1, Emily Leede1, Lawrence H Brown1
1Department of Surgery and Perioperative Care, Dell Seton Medical Center at the University of Texas, 1500 Red River St, Austin, TX, 78701, USA.
Current risk scoring models fail to reliably identify pulmonary embolisms (PE) in trauma patients. Further research is needed to improve diagnostic accuracy for post-traumatic PE.
Area of Science:
- Trauma care
- Cardiovascular diagnostics
- Pulmonary medicine
Background:
- Post-traumatic pulmonary embolism (PE) poses a diagnostic challenge.
- Identifying reliable risk factors and scoring models for PE in trauma is crucial.
Purpose of the Study:
- To evaluate the effectiveness of existing risk scoring models in identifying PE in trauma patients.
- To identify potential risk factors for post-traumatic PE.
Main Methods:
- Retrospective review of adult trauma patients who underwent CT pulmonary angiogram (CTPA) for suspected PE.
- Systematic literature search for eleven established PE risk scoring models.
- Application and comparison of identified risk scoring models to the patient cohort.
Main Results:
- 13% of trauma patients (31/235) receiving CTPA were diagnosed with PE.
- No evaluated risk scoring model achieved >90% sensitivity and specificity for PE detection.
- The Wells Score demonstrated the highest area under the curve (0.65); however, logistic regression revealed no independent association between its variables and PE.
Conclusions:
- Existing clinical variables and risk scoring models are insufficient for differentiating PE in trauma patients.
- Current diagnostic tools lack the necessary accuracy for suspected PE in this population.
Related Concept Videos
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
Pulmonary Embolism I: Introduction
Pulmonary Embolism III: Nursing Management

