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Treatment for Pulmonary Arterial Hypertension: Prostacyclin Receptor Agonists01:23

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Prostacyclin receptor agonists are a class of therapeutic agents integral to managing pulmonary arterial hypertension (PAH). These drugs operate by mimicking the action of prostaglandin I2, or PGI2, a naturally occurring compound in the body.
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New Advancements in Inflatable Penile Prosthesis.

Brian F Dinerman1, Leon Telis1, Jean Francois Eid2

  • 1Department of Urology, Lenox Hill Hospital, Zucker School of Medicine at Hofstra/Northwell, New York, NY.

Sexual Medicine Reviews
|February 21, 2021
PubMed
Summary
This summary is machine-generated.

Recent advancements in inflatable penile prosthesis (IPP) technology have improved device concealability and surgical outcomes. These innovations enhance patient quality of life for erectile dysfunction treatment.

Keywords:
Erectile DysfunctionInfectionInflatable Penile ProsthesisReviewTransgender

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Area of Science:

  • Urology
  • Medical Device Technology
  • Sexual Medicine

Background:

  • Inflatable penile prosthesis (IPP) is a primary treatment for erectile dysfunction resistant to other therapies.
  • Technological progress has focused on improving 3-piece IPP designs for better concealment and surgical ease since the 1980s.

Purpose of the Study:

  • To review the latest technological updates in inflatable penile prosthesis (IPP) devices.
  • To examine recent research on IPP innovations and their functional outcomes.
  • To incorporate over 32 years of surgical and postoperative management experience.

Main Methods:

  • Literature review of studies published in the last 10 years (up to March 2020).
  • Focus on technical advancements in IPP components: pump, reservoir, tubing, and cylinders.
  • Inclusion of anti-infective coatings, transgender innovations, and postoperative care.

Main Results:

  • New designs feature improved discreteness (flat reservoir) and optimized tubing.
  • Advancements include one-touch deflation, narrow cylinders, and improved cylinder-to-tubing angles for easier placement.
  • Innovations also include anatomically designed cylinder tips and IPPs for neophallus construction; submuscular reservoir placement is FDA-approved.

Conclusions:

  • Penile prosthesis technology has evolved to enhance function, usability, and reduce complications.
  • IPP implantation significantly improves patient outcomes.
  • Surgeons must stay updated on IPP advancements for optimal patient care.