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Updated: Nov 16, 2025

An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota
Published on: July 31, 2019
Epigenetic Regulation of Gut Microbial Dysbiosis
Shivani Srivastava1, Archana Singh2, Kumar Sandeep3
1Department of Physiology and Cell Biology, Wexner Medical Center, Davis Heart and Lung Research Institute, Ohio State University, Columbus, OH 43201 USA.
Abstract:
Microbiota inside the gut plays a vital role in maintaining human health. Microbial dysbiosis is associated with various complications leading to a range of diseases. Epigenetic changes enforced by various environmental and lifestyle factors lead to heritable modifications. These epigenetic modifications include DNA methylation, histone modifications, chromatin remodelling, and ribonucleic acid-based mechanisms. This review summarizes the impacts of environmental factors on the gut microbiome, epigenetic modifications, and their role in cardiovascular diseases.
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