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Updated: Nov 16, 2025

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
Published on: November 10, 2023
Review of potential risk groups for coronavirus disease 2019 (COVID-19)
M Naveed1, M Naeem2, M Ur Rahman3
1Institute of Microbiology, School of Life Sciences, Lanzhou University, Tianshui Road No. 222, Lanzhou, 730000, China.
Insights
This review identifies high-risk groups for coronavirus disease 19 (COVID-19), including older adults and those with comorbidities. Recommendations like vaccination and lockdowns aim to reduce severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission.
Area of Science:
- Public Health
- Infectious Diseases
- Epidemiology
Background:
- Coronavirus disease 19 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), presents a significant global health challenge.
- Older adults and individuals with underlying health conditions (comorbidities) face increased risks of severe illness and mortality from COVID-19.
Purpose of the Study:
- To identify specific populations at higher risk for COVID-19.
- To outline strategies for mitigating community transmission of SARS-CoV-2.
Main Methods:
- This review synthesizes existing research on COVID-19 risk factors and transmission.
- Analysis of epidemiological data to pinpoint vulnerable groups.
Main Results:
- High-risk groups include healthcare workers, smokers, older adults, travelers, and pregnant women.
- Patients with cardiovascular disease, hypertension, diabetes, respiratory illness, and cancer are at elevated risk for severe COVID-19 outcomes and mortality.
Conclusions:
- Targeted interventions and protective measures are crucial for diminishing the threat of SARS-CoV-2 infection.
- Recommendations include vaccination, consistent hand hygiene with sanitizers, and adherence to lockdown measures to break the chain of transmission.
Abstract:
The current pandemic of coronavirus disease 19 (COVID-19) is a global issue caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Studies have revealed that this virus results in poorer consequences and a higher rate of mortality in older adults and those with comorbidities such as cardiovascular disease, hypertension, diabetes and prolonged respiratory illness. In this review, we discuss in detail the potential groups at risk of COVID-19 and outline future recommendations to mitigate community transmission of COVID-19. The rate of COVID-19 was high in healthcare workers, smokers, older adults, travellers and pregnant women. Furthermore, patients with severe medical complications such as heart disease, hypertension, respiratory illness, diabetes mellitus and cancer are at higher risk of disease severity and mortality. Therefore, special effort and devotion are needed to diminish the threat of SARS-CoV-2 infection. Proper vaccination, use of sanitizers for handwashing and complete lockdown are recommended to mitigate the chain of COVID-19 transmission.
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