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Co-epidemics: have measures against COVID-19 helped to reduce Lassa fever cases in Nigeria?
R C Reuben1, S D Gyar2, M D Makut2
1German Centre for Integrative Biodiversity Research (iDiv), Halle-Jena-Leipzig, Germany.
Insights
The COVID-19 pandemic unexpectedly reduced Lassa fever cases in Nigeria due to implemented infection control measures. Further research is needed to understand the interaction between these two epidemics.
Area of Science:
- Epidemiology
- Infectious Diseases
- Public Health
Background:
- Nigeria faces concurrent epidemics of COVID-19 and Lassa fever.
- Clinical similarities between COVID-19 and Lassa fever pose diagnostic challenges and risk of co-infection.
- The Lassa fever epidemic is recurrent in West Africa.
Purpose of the Study:
- To investigate the impact of COVID-19 infection prevention and control (IPC) measures on Lassa fever epidemiology in Nigeria.
- To understand the interaction and evolutionary dynamics between Lassa fever and COVID-19.
- To analyze the abrupt changes in Lassa fever data during the COVID-19 pandemic.
Main Methods:
- Observational study analyzing epidemiological data of Lassa fever.
- Comparison of Lassa fever case numbers before and after the implementation of COVID-19 IPC measures.
- Assessment of national, sub-national, and community-level IPC strategies.
Main Results:
- Implementation of COVID-19 IPC measures led to a concurrent reduction in Lassa fever cases across Nigeria.
- The strict adherence to infection control protocols for COVID-19 influenced Lassa fever transmission dynamics.
- Significant changes in Lassa fever epidemiological patterns were observed.
Conclusions:
- COVID-19 IPC measures had an unintended positive effect on controlling Lassa fever transmission in Nigeria.
- Further investigation is crucial to fully elucidate the interplay between these two diseases and the long-term effects.
- Understanding these interactions is vital for future public health strategies in West Africa.
Abstract:
While the coronavirus disease 2019 (COVID-19) pandemic has multiple devastating public health and socio-economic effects across the world, Nigeria along with other West African countries is simultaneously faced with a recurrent Lassa fever epidemic. The complicating scenario is the similarity in the clinical manifestation of COVID-19 and Lassa fever, making the misdiagnosis of the initial presentation of both diseases a significant risk with an increased likelihood of co-infection. However, the strict implementation of COVID-19 infection prevention and control measures across Nigeria after the initial outbreaks concurrently resulted in the reduction of Lassa fever cases. The abrupt change in the behaviour of Lassa fever epidemiological data, which are attributable to the implementation of COVID-19 infection prevention and control measures at the national, sub-national and community levels, requires detailed investigation during and after the COVID-19 epidemic to elucidate the interactions and evolutionary dynamics of Lassa fever cases in Nigeria.

