Gallstone Frequency in Children With Celiac Disease
1Pediatric Gastroenterology, Van Education and Research Hospital, Van, TUR.
Cureus
|February 22, 2021
Summary
Children with celiac disease (CD) have a higher incidence of gallstones. Early diagnosis and gluten-free diet management of CD may prevent gallstone development in pediatric patients.
Area of Science:
- Gastroenterology
- Immunology
- Pediatrics
Background:
- Celiac disease (CD) is an autoimmune disorder triggered by gluten in genetically predisposed individuals.
- It involves a T cell-driven immune response affecting the small intestine.
Purpose of the Study:
- To investigate the frequency of gallstones in children diagnosed with celiac disease.
- To assess the association between celiac disease and gallstone formation in pediatric patients.
Main Methods:
- A comparative study included 120 children with CD and 100 healthy controls.
- Abdominal ultrasonography was used to detect gallstones; relevant clinical and laboratory data were analyzed.
Main Results:
- Gallstones were found in 5% of children with CD, compared to 3% in the control group.
- Celiac disease was diagnosed in 1.3% of patients initially presenting with gallstones.
Conclusions:
- Celiac disease is associated with an increased risk of gallstone development in children.
- Early diagnosis and treatment of CD, including a gluten-free diet, are crucial for preventing gallstones.
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