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Published on: February 1, 2022
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Graphene and its Derivatives-Based Optical Sensors
Xiao-Guang Gao1,2, Ling-Xiao Cheng3, Wen-Shuai Jiang4
1College of Biomedical Engineering, Taiyuan University of Technology, Taiyuan, China.
Frontiers in Chemistry
|February 22, 2021
Summary
Graphene and its derivatives are revolutionizing optical sensors with high sensitivity and fast response. This review highlights their use in fluorescence, SERS, and fiber optic biosensors for applications like cancer diagnosis.
Area of Science:
- Materials Science
- Nanotechnology
- Sensor Technology
Background:
- Graphene, the first 2D material, offers unique properties like broadband light absorption and fluorescence quenching.
- Graphene derivatives are emerging as versatile platforms for advanced optical sensors.
- These sensors exhibit high sensitivity, low cost, rapid response, and miniaturization potential.
Purpose of the Study:
- To review recent advancements in graphene and its derivatives-based optical sensors.
- To cover key applications including fluorescence sensing, SERS, and optical fiber biosensors.
- To discuss diverse sensing applications such as single-cell detection, cancer diagnosis, and biomolecule sensing.
Main Methods:
- Comprehensive literature review of graphene-based optical sensor research.
- Analysis of sensor performance metrics and application scope.
- Discussion of sensing mechanisms and technological integration.
Main Results:
- Graphene and derivatives enable high-performance optical sensors with enhanced sensitivity and speed.
- Successful applications demonstrated in fluorescence, SERS, and optical fiber biosensing.
- Significant progress in detecting cancer biomarkers, proteins, and DNA at the molecular level.
Conclusions:
- Graphene-based optical sensors offer a promising future for sensitive and rapid diagnostics.
- Further research can optimize sensor design and expand applications in healthcare and environmental monitoring.
- A roadmap for future trends in graphene optical sensor development is presented.

