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Published on: June 8, 2017
Imaging features of rhinocerebral mucormycosis: from onset to vascular complications
Linda Mazzai1, Mariagiulia Anglani2, Chiara Giraudo3
1Neuroradiology UOC, Department of Diagnostics, San Bortolo Vicenza Hospital, Vicenza, Italy.
Abstract:
Rhinocerebral mucormycosis (RCM) may result in severe intracranial ischemic and hemorrhagic lesions. Both computed tomography (CT) and magnetic resonance imaging (MRI) play an essential role in the diagnosis of RCM, but whereas CT is better for assessing bone erosion, MRI is superior in evaluating soft tissue, intraorbital extension, and in assessing intracranial and vascular invasion. Specific CT and MRI techniques, such as CT angiography or enhanced MR angiography, and more advanced MRI sequences such as gadolinium-3D Black Blood imaging, contribute to the assessment of the extension of vascular invasion.In this pictorial review, we describe specific CT and MRI signs of RCM, mainly focusing on its life-threatening complications due to vascular involvement.
Insights
Rhinocerebral mucormycosis (RCM) can cause severe brain lesions. This review highlights computed tomography (CT) and magnetic resonance imaging (MRI) signs of RCM, focusing on vascular complications.
Area of Science:
- Radiology
- Infectious Diseases
- Neurology
Background:
- Rhinocerebral mucormycosis (RCM) is a severe fungal infection.
- RCM can lead to dangerous intracranial ischemic and hemorrhagic lesions.
Purpose of the Study:
- To describe computed tomography (CT) and magnetic resonance imaging (MRI) findings in RCM.
- To focus on RCM's life-threatening vascular complications.
Main Methods:
- Pictorial review of RCM cases.
- Analysis of CT and MRI imaging features.
- Evaluation of advanced CT and MRI techniques for vascular assessment.
Main Results:
- CT excels in evaluating bone erosion in RCM.
- MRI is superior for soft tissue, orbital, intracranial, and vascular invasion assessment.
- Advanced CT/MRI angiography aids in evaluating vascular invasion extent.
Conclusions:
- CT and MRI are crucial for RCM diagnosis.
- Imaging plays a key role in assessing RCM's vascular complications and extent.
- Early detection of vascular invasion is vital for RCM management.

