Therapy of primary diffuse large cell lymphoma of the penis with preservation of function

Only 7 cases of primary lymphoma of the penis have been described previously. We report a case of diffuse large cell lymphoma of the glans penis. The clinical features, histology and management of these cases are reviewed. The previously reported cases were treated with surgical resection or radiotherapy resulting in some degree of local morbidity. Our patient achieved complete remission after only 1 cycle of chemotherapy. The benefits of chemotherapy over surgery or radiotherapy for primary lymphoma of the penis are discussed.