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Updated: Nov 16, 2025

Use of In vivo Imaging to Monitor the Progression of Experimental Mouse Cytomegalovirus Infection in Neonates
Published on: July 6, 2013
How can the latent cytomegalovirus cause an increase in all-cause mortality? An answer based on the microcompetition
1Department of Internal Medicine, University of California, San Diego, San Diego, CA, USA.
Abstract:
Many studies showed the existence of a positive association between cytomegalovirus (CMV) seropositivity and all-cause mortality. In this paper, we use the microcompetition model to explain how the latent CMV sequesters the limiting GABP∙p300/CBP transcription complex, which causes abnormal cellular gene expression, a chronic disease and mortality. Since most people harbour the latent CMV, we urge further research on this topic.
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