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Updated: Nov 16, 2025

Laparoscopic Left Hemihepatectomy Combined with Caudate Lobe Resection
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Laparoscopic isolated caudate lobe resection.

Maulik Parikh1, Ho-Seong Han2, Jai Young Cho3

  • 1Shreemay Gastrosurgical Hospital, "Sameep", Plot No 98, Kalubha Road, Kalanala, Bhavnagar, Gujarat, 364002, India.

Scientific Reports
|February 23, 2021
PubMed
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Laparoscopic isolated caudate lobectomy is a feasible and safe surgical option for selected patients, comparable to open surgery. This minimally invasive technique shows similar outcomes in operation time, blood loss, hospital stay, and survival rates.

Area of Science:

  • Hepatobiliary Surgery
  • Minimally Invasive Surgery
  • Surgical Oncology

Background:

  • Isolated caudate lobectomy is a complex surgical procedure, historically performed infrequently and often combined with resection of other liver segments.
  • The caudate lobe's anatomical location presents unique surgical challenges, making its isolated resection demanding even for experienced surgeons.

Purpose of the Study:

  • To evaluate the feasibility, safety, and outcomes of laparoscopic isolated caudate lobectomy.
  • To compare the results of laparoscopic isolated caudate lobectomy with those of the traditional open surgical technique.

Main Methods:

  • A retrospective analysis of 21 patients who underwent isolated caudate lobectomy (anatomical or non-anatomical) between January 2005 and December 2018.
  • Patients were categorized into two groups: laparoscopic surgery (12 patients) and open surgery (9 patients).

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  • Comparison of intra-operative and postoperative outcomes, including operation time, estimated blood loss, hospital stay, complication rates, and survival rates, with a median follow-up of 43 months.

    • Main Results:

    • Operation time, estimated blood loss, and hospital stay were comparable between the laparoscopic and open groups (p > 0.05).
    • The overall postoperative complication rates were similar between the two surgical approaches (p = 0.375).
    • Five-year disease-free survival (42.9% vs. 60.0%) and overall survival rates (76.2% vs. 64.8%) did not significantly differ between laparoscopic and open caudate lobectomy (p > 0.05).

    Conclusions:

    • Laparoscopic isolated caudate lobectomy is a feasible and safe procedure for selected patients.
    • Surgical expertise and technological advancements have made minimally invasive approaches to caudate lobe resection viable.
    • The outcomes of laparoscopic isolated caudate lobectomy are comparable to those of open surgery, offering a potentially less invasive alternative.