The effect of automated oxygen control on clinical outcomes in preterm infants: a pre- and post-implementation cohort
H H Salverda1, N J Oldenburger2, M Rijken2
1Division of Neonatology, Department of Paediatrics, Leiden University Medical Center, PO box 9600, 2300 RC, Leiden, The Netherlands. H.H.Salverda@lumc.nl.
Automated oxygen control (AOC) in preterm infants did not change mortality or complications. However, it reduced invasive ventilation duration, showing a shift towards non-invasive support in neonatal intensive care units.
Area of Science:
- Neonatal Medicine
- Pediatric Critical Care
- Respiratory Support
Background:
- Oxygen saturation deviations are linked to mortality and morbidities in preterm infants.
- Automated oxygen control (AOC) improves time within target oxygen saturation ranges.
Purpose of the Study:
- To compare clinical outcomes in preterm infants before and after implementing AOC as standard care.
- To evaluate the impact of AOC on mortality, prematurity complications, ventilation duration, and NICU length of stay.
Main Methods:
- Retrospective pre-post implementation cohort study.
- Inclusion of preterm infants (24-29 weeks gestational age) receiving respiratory support.
- Comparison of outcomes between infants before (2012-2015) and after (2015-2018) AOC implementation.
Main Results:
- No significant differences in mortality or prematurity complications between cohorts.
- Shorter duration of invasive ventilation in the AOC group (4.7 days) compared to the pre-AOC group (6.4 days).
- No difference in Neonatal Intensive Care Unit (NICU) length of stay, but a trend towards increased non-invasive ventilation post-implementation.
Conclusions:
- Implementation of AOC as standard care did not alter mortality or morbidity in preterm infants during admission.
- AOC use was associated with a reduction in invasive ventilation days.
- A shift towards non-invasive ventilation strategies was observed after AOC implementation.
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