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Related Concept Videos

Proteomics01:33

Proteomics

8.8K
A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
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Protein Networks02:26

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An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
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mRNA Interactome Capture from Plant Protoplasts
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Mapping the plant proteome: tools for surveying coordinating pathways.

Amanda L Smythers1, Leslie M Hicks1

  • 1Department of Chemistry, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, U.S.A.

Emerging Topics in Life Sciences
|February 23, 2021
PubMed
Summary

Plant proteomics research uses advanced mass spectrometry to study protein signaling and interactions, crucial for adapting to environmental changes and ensuring food security.

Keywords:
plant proteinspost translational modificationprotein–protein interactionsproteomics

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Area of Science:

  • Plant biology
  • Proteomics
  • Biochemistry

Background:

  • Plants exhibit complex regulatory mechanisms for environmental adaptation, involving protein post-translational modifications and interactions.
  • Understanding plant proteomic networks is vital for addressing global challenges like food security and climate change.

Purpose of the Study:

  • To review recent advancements in plant proteomics, focusing on spatially and temporally resolved analyses.
  • To highlight the importance of a comprehensive plant cell atlas.

Main Methods:

  • Mass spectrometry-based proteomics enables deep investigations into plant protein signaling.
  • Techniques are increasingly optimized for plant systems, allowing detailed analysis of post-translational modifications and protein interactions.

Main Results:

  • Recent technological advances facilitate unprecedented depth in plant proteomic studies.
  • Spatially and temporally resolved analyses of post-translational modifications and protein interactions are advancing.

Conclusions:

  • Continued advancements in plant proteomics are essential for understanding plant responses to environmental fluctuations.
  • The development of a comprehensive plant cell atlas is a critical next step in the field.