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Predicting Self-Rated Health Across the Life Course: Health Equity Insights from Machine Learning Models
Cheryl R Clark1,2,3, Mark J Ommerborn4, Kaitlyn Moran4
1Center for Community Health and Health Equity, Brigham and Women's Hospital, 1620 Tremont Street, Boston, MA 02120, Boston, MA, USA. crclark@partners.org.
Background:
Self-rated health is a strong predictor of mortality and morbidity. Machine learning techniques may provide insights into which of the multifaceted contributors to self-rated health are key drivers in diverse groups.
Objective:
We used machine learning algorithms to predict self-rated health in diverse groups in the Behavioral Risk Factor Surveillance System (BRFSS), to understand how machine learning algorithms might be used explicitly to examine drivers of self-rated health in diverse populations.
Design:
We applied three common machine learning algorithms to predict self-rated health in the 2017 BRFSS survey, stratified by age, race/ethnicity, and sex. We replicated our process in the 2016 BRFSS survey.
Participants:
We analyzed data from 449,492 adult participants of the 2017 BRFSS survey.
Main Measures:
We examined area under the curve (AUC) statistics to examine model fit within each group. We used traditional logistic regression to predict self-rated health associated with features identified by machine learning models.
Key Results:
Each algorithm, regularized logistic regression (AUC: 0.81), random forest (AUC: 0.80), and support vector machine (AUC: 0.81), provided good model fit in the BRFSS. Predictors of self-rated health were similar by sex and race/ethnicity but differed by age. Socioeconomic features were prominent predictors of self-rated health in mid-life age groups. Income [OR: 1.70 (95% CI: 1.62-1.80)], education [OR: 2.02 (95% CI: 1.89, 2.16)], physical activity [OR: 1.52 (95% CI: 1.46-1.58)], depression [OR: 0.66 (95% CI: 0.63-0.68)], difficulty concentrating [OR: 0.62 (95% CI: 0.58-0.66)], and hypertension [OR: 0.59 (95% CI: 0.57-0.61)] all predicted the odds of excellent or very good self-rated health.
Conclusions:
Our analysis of BRFSS data show social determinants of health are prominent predictors of self-rated health in mid-life. Our work may demonstrate promising practices for using machine learning to advance health equity.
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