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Regenerative Therapy Using Umbilical Cord Serum.

Nagarajan Maharajan1,2, Gwang-Won Cho1,2, Ji Hyun Choi3

  • 1Department of Biology, College of Natural Science, Chosun University, Gwangju, Republic of Korea.

In Vivo (Athens, Greece)
|February 24, 2021
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Summary

Umbilical cord serum (UCS) offers a rich source of growth factors for regenerative medicine. Its applications include treating eye conditions and regenerating tissues, presenting a cost-effective alternative to fetal bovine serum in cell culture.

Keywords:
Umbilical cord serumcytokinesgrowth factorsregenerationreview

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Area of Science:

  • Regenerative Medicine
  • Biomaterials
  • Cell Therapy

Background:

  • Umbilical cord serum (UCS) is derived from cord blood, containing growth factors and active molecules.
  • Serum can be prepared from various blood sources for therapeutic use.

Purpose of the Study:

  • To review the role of umbilical cord serum in regenerative therapy.
  • To highlight the clinical applications of UCS.

Main Methods:

  • Review of existing literature on UCS applications.
  • Analysis of UCS properties for regenerative medicine and cell culture.

Main Results:

  • UCS eye drops treat dry eye, burns, glaucoma, and keratitis.
  • UCS combined with biomaterials aids tissue regeneration (tympanic membrane, bone, nerve).
  • UCS is a safe, cost-effective alternative to fetal bovine serum in cell culture due to lack of pathogens and xenoproteins.

Conclusions:

  • Umbilical cord serum is a versatile product for regenerative medicine.
  • UCS demonstrates significant potential in various clinical and research applications.