Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Somatosensation

Somatosensation

The somatosensory system relays sensory information from the skin, mucous membranes, limbs, and joints. Somatosensation is more familiarly known as the sense of touch. A typical somatosensory pathway includes three types of long neurons: primary, secondary, and tertiary. Primary neurons have cell bodies located near the spinal cord in groups of neurons called dorsal root ganglia. The sensory neurons of ganglia innervate designated areas of skin called dermatomes.

Spinal Nerves: Plexus I

Spinal Nerves: Plexus I

Nerve plexuses are networks of interlacing nerves that serve as communication hubs to distribute and organize nerve action across various body regions. The nerve plexuses are organized into the cervical plexus located in the neck region, brachial plexus in the shoulder area, lumbar plexus found in the lower back, sacral plexus situated in the pelvis, and coccygeal plexus located in the coccygeal region.
The Cervical Plexus
The cervical plexus, formed by the anterior rami of the first four...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Correction: Antioxidant Effect of Naringin Demonstrated Through a Bayes' Theorem Driven Multidisciplinary Approach Reveals its Prophylactic Potential as a Dietary Supplement for Ischemic Stroke.

Molecular neurobiology·2025

Same author

Antioxidant Effect of Naringin Demonstrated Through a Bayes' Theorem Driven Multidisciplinary Approach Reveals its Prophylactic Potential as a Dietary Supplement for Ischemic Stroke.

Molecular neurobiology·2024

Same author

Receptor for Advanced Glycation End Product, Organ Crosstalk, and Pathomechanism Targets for Comprehensive Molecular Therapeutics in Diabetic Ischemic Stroke.

Biomolecules·2022

Same author

Mononeuritis Multiplex as Initial Manifestation of Pure Neuritic Leprosy-A Forgotten Cause: Clinical, Electrodiagnostic and Pathologic Correlations.

Neurology India·2020

Same author

Hyperacute Paraplegia and Neurovascular (Immuno Vasculotoxic) Catastrophe of Nicolau Syndrome: Primum Non nocere.

Annals of Indian Academy of Neurology·2019

Same author

Preventing "Neurophobia": Remodeling Neurology Education for 21<sup>st</sup>-Century Medical Students through Effective Pedagogical Strategies for "Neurophilia".

Annals of Indian Academy of Neurology·2018

Search research articles

Related Experiment Video

Updated: Nov 16, 2025

Structured Motor Rehabilitation After Selective Nerve Transfers

Structured Motor Rehabilitation After Selective Nerve Transfers

Published on: August 15, 2019

Selective Hand Motor Cortex Lesions Masquerading as "Pseudoperipheral Nerve Palsy".

Bhaskara P Shelley¹, Prakash Harishchandra², Acharya K Devadas³

¹Department of Neurology, Yenepoya Medical College, Yenepoya (Deemed to Be) University, Mangalore, Karnataka, India.

Annals of Indian Academy of Neurology

|February 24, 2021

Summary

Acute hand weakness mimicking peripheral nerve damage requires careful clinical evaluation. Central hand motor cortex lesions can present as "pseudoperipheral palsy," necessitating broader differential diagnoses beyond stroke.

Keywords:

Diffusion-weighted imaging Giant cell arteritis cerebral metastasis stroke common carotid artery thrombosis hand motor cortex hyperhomocysteinemia iron-deficiency anemia magnetic resonance imaging precentral hand knob area pseudomedian nerve palsy pseudoperipheral palsy pure motor weakness stroke chameleon stroke masquerader

More Related Videos

Behavioral Assessment of Manual Dexterity in Non-Human Primates

Behavioral Assessment of Manual Dexterity in Non-Human Primates

Published on: November 11, 2011

A Mouse Model of Direct Anastomosis via the Prespinal Route for Crossing Nerve Transfer Surgery

A Mouse Model of Direct Anastomosis via the Prespinal Route for Crossing Nerve Transfer Surgery

Published on: October 19, 2021

Related Experiment Videos

Last Updated: Nov 16, 2025

Structured Motor Rehabilitation After Selective Nerve Transfers

Structured Motor Rehabilitation After Selective Nerve Transfers

Published on: August 15, 2019

Behavioral Assessment of Manual Dexterity in Non-Human Primates

Behavioral Assessment of Manual Dexterity in Non-Human Primates

Published on: November 11, 2011

A Mouse Model of Direct Anastomosis via the Prespinal Route for Crossing Nerve Transfer Surgery

A Mouse Model of Direct Anastomosis via the Prespinal Route for Crossing Nerve Transfer Surgery

Published on: October 19, 2021

Area of Science:

Neurology
Neuroscience
Clinical Medicine

Background:

Distinguishing acute distal upper limb pure motor weakness from peripheral nerve deficits is crucial.
Pseudoperipheral palsy, a rare phenotype imitating peripheral nerve damage, can arise from central hand motor cortex lesions.

Observation:

This study examines six patients with central hand motor cortex lesions presenting as pseudomedian, pseudoradial, or pseudoulnar nerve palsies.
The phenotype, previously attributed solely to cortical cerebral infarction, was observed in diverse etiologies.

Findings:

Etiologies included stroke, hyperhomocysteinemia, carotid artery thrombosis, iron-deficiency anemia, giant cell arteritis, cerebral metastasis, and cardiac conditions.
These findings expand the known causes of central hand weakness beyond ischemic stroke.

Implications:

Physicians must recognize the varied presentations of central hand motor cortex lesions.
Familiarity with these peculiar clinical presentations aids in accurate diagnosis and management of central neurological deficits affecting hand function.