Related Experiment Videos
MELAS syndrome: characteristic migrainous and epileptic features and maternal transmission
P Montagna1, R Gallassi, R Medori
1Institute of Neurology, University of Bologna, Italy.
Neurology
|May 1, 1988
Abstract:
Severe prolonged migrainous symptoms and prolonged partial status epilepticus are characteristic features of the MELAS syndrome (mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes). Maternal transmission previously found in myoclonus epilepsy and ragged-red fibers (MERRF), another mitochondrial disease, is suggested in this disorder as well.
Insights
Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome presents with severe migraines and prolonged seizures. Evidence suggests maternal transmission, similar to other mitochondrial disorders like MERRF.
Area of Science:
- Neurology
- Genetics
- Mitochondrial Diseases
Background:
- MELAS syndrome is characterized by severe migrainous symptoms and prolonged partial status epilepticus.
- Mitochondrial diseases share common features, including potential maternal transmission patterns.