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Sleeve Gastrectomy in Mice using Surgical Clips
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Optimizing Multivitamin Supplementation for Sleeve Gastrectomy Patients.

Laura Heusschen1,2, Agnes A M Berendsen3, Mellody I Cooiman4

  • 1Department of Bariatric Surgery, Vitalys, part of Rijnstate Hospital, PO box 9555, 6800, Arnhem, The Netherlands. LHeusschen@Rijnstate.nl.

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PubMed
Summary

A specialized multivitamin (WLS Optimum 2.0) effectively prevents micronutrient deficiencies after sleeve gastrectomy (SG). Lifelong supplementation is recommended, but patient compliance and monitoring remain crucial for optimal nutritional status.

Keywords:
Bariatric surgeryDeficienciesMetabolic surgeryMicronutrientsMineralsMorbid obesitySleeve gastrectomy (SG)SupplementationVitamins

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Area of Science:

  • Bariatric surgery outcomes
  • Nutritional science
  • Gastroenterology

Background:

  • Sleeve gastrectomy (SG) often leads to micronutrient deficiencies.
  • Lifelong daily multivitamin supplementation is standard post-SG.
  • Previous studies informed the development of optimized supplements for SG patients.

Purpose of the Study:

  • To evaluate the short-term effectiveness of an optimized specialized multivitamin supplement (WLS Optimum 2.0) for sleeve gastrectomy patients.
  • To compare the efficacy of WLS Optimum 2.0 against a previous formulation (WLS Optimum 1.0).

Main Methods:

  • An open-label study involving 76 patients receiving WLS Optimum 2.0 for 12 months.
  • Comparison with a historical cohort of 75 patients who received WLS Optimum 1.0 for 12 months.
  • Intention-to-treat analysis was performed.

Main Results:

  • The WLS Optimum 2.0 group showed higher serum levels of vitamin B12, vitamin B6, and zinc, with lower deficiency rates for vitamin B12 and phosphate.
  • The WLS Optimum 1.0 group had higher MCV and serum folic acid levels.
  • Greater increases in serum phosphate, vitamin B6, and zinc were observed in the WLS Optimum 2.0 group over 12 months.

Conclusions:

  • Specialized multivitamins are effective in preventing most vitamin and mineral deficiencies in sleeve gastrectomy patients, particularly when compliant.
  • Ongoing monitoring of nutritional status and patient compliance is essential.
  • WLS Optimum 2.0 demonstrates effectiveness in improving key micronutrient levels post-SG.