Related Experiment Video
Updated: Jul 23, 2026

Measurement of Fronto-limbic Activity Using an Emotional Oddball Task in Children with Familial High Risk for Schizophrenia
Published on: December 2, 2015
Dorsal anterior cingulate cortex intrinsic functional connectivity linked to electrocortical measures of error
Hayley Gilbertson1, Lin Fang1, Jeremy A Andrzejewski1
1Department of Psychological Science, Northern Michigan University, Marquette, MI, USA.
Abstract:
The error-related negativity (ERN) is a response-locked event-related potential, occurring approximately 50 ms following an erroneous response at frontocentral electrode sites. Source localization and functional magnetic resonance imaging (fMRI) research indicate that the ERN is likely generated by activity in the dorsal anterior cingulate cortex (dACC). The dACC is thought to be a part of a broader network of brain regions that collectively comprise an error monitoring network. However, little is known about how intrinsic connectivity within the dACC-based error monitoring network contributes to variability in ERN amplitude. The purpose of this study was to assess the relationship between dACC functional connectivity and ERN amplitude. In a sample of highly trait anxious individuals, the ERN was elicited in a flanker task and functional connectivity was assessed in a 10-min resting-state fMRI scan. Results suggest that the strength of dACC seeded functional connectivity with the supplementary motor area is correlated with the ΔERN (i.e., incorrect-correct responses) amplitude such that greater ΔERN amplitude was accompanied by greater functional coupling between these regions. In sum, ERN amplitude appears to be related to the strength of functional connectivity between error monitoring and motor control regions of the brain.
More Related Videos
09:00Investigating the Function of Deep Cortical and Subcortical Structures Using Stereotactic Electroencephalography: Lessons from the Anterior Cingulate Cortex
Published on: April 15, 2015
09:14Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
Published on: March 14, 2025
Related Concept Videos
Association Areas of the Cortex
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
Role of Cerebellum and Prefrontal Cortex in Memory