Related Experiment Video
Updated: Nov 16, 2025

02:21
Microscopic Electric Rotary Grinding of Plaques Combined with Graft Repair in the Management of Peyronie's Disease
Published on: March 15, 2024
1.1K
Pyoderma gangrenosum of the penis
Justin Loloi1, Susan M MacDonald
1Department of Urology, Montefiore Medical Center, Bronx, New York, USA.
The Canadian Journal of Urology
|February 24, 2021
Summary
Pyoderma gangrenosum (PG) is a rare inflammatory skin condition causing painful ulcers. This case details a unique penile PG presentation and successful treatment with steroids and methotrexate.
Area of Science:
- Dermatology
- Urology
Background:
- Pyoderma gangrenosum (PG) is a rare inflammatory skin disorder.
- Isolated penile PG is exceptionally uncommon, with few reported cases.
Observation:
- A 71-year-old man presented with a nonhealing, destructive penile ulcer.
- Extensive workup was required to establish the diagnosis of PG.
Findings:
- The patient's penile ulceration was diagnosed as pyoderma gangrenosum.
- Systemic steroids and methotrexate effectively halted disease progression.
Implications:
- Early recognition of penile PG is crucial for managing this potentially devastating condition.
- This case underscores the importance of considering PG in nonhealing penile ulcers.
- Effective management strategies include systemic corticosteroids and immunosuppressants like methotrexate.
More Related Videos
Related Concept Videos
Penis
14.7K
The penis serves a dual role in sexual reproduction and urination. It consists of three main regions: the glans penis, the body, and the root, each with distinct functions and unique anatomical features.
Anatomy of the Penis
The glans penis, or the head, is the terminal part of the penis and houses the external urethral orifice, the exit point for urine and semen. Covered by the prepuce, or foreskin, the glans is noted for its sensitivity and plays a key role in sexual pleasure. The body of the...
Anatomy of the Penis
The glans penis, or the head, is the terminal part of the penis and houses the external urethral orifice, the exit point for urine and semen. Covered by the prepuce, or foreskin, the glans is noted for its sensitivity and plays a key role in sexual pleasure. The body of the...
14.7K
Skin Diseases and Disorders
4.7K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
4.7K
Peripheral Artery Disease I: Introduction
147
Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...
147
Sexually Transmitted Infections
570
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
570
Disorders of the Male Reproductive System
3.7K
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
3.7K
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
163
Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
163

