[Characteristics of disorders of carbohydrate metabolism in rats with stress]

The purpose was to study the effect of stress caused by cavitary operation (the 1st group) and stress resulting from suspending animals at the neck skin fold for 2, 4, 12 and 24 h (the 2nd group) on the development of metabolic diabetic shifts in rats. Postoperative stress was accompanied by a decrease in motor activity of rats and sispension caused intense muscular activity aimed at getting free. All elements of the diabetic syndrome expressed in glucose intolerance, reduction of sensitivity to insulin, reduced insulin action on glucose oxidation in adipose tissue, hyperinsulinemia and a rise of basal glycemia, were revealed in rats with postoperative stress; in rats of the 2nd group they were undetectable. It could be accounted for by muscular activity of animals in these groups.