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Techniques for the Evolution of Robust Pentose-fermenting Yeast for Bioconversion of Lignocellulose to Ethanol
Published on: October 24, 2016
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Dual identities for various alcohols in two different yeasts
Nitin Mahendra Chauhan1, S Mohan Karuppayil2
1College of Natural and Computational Sciences, Dilla University, Dilla, Ethiopia.
Mycology
|February 25, 2021
Summary
Yeast use chemical signals like farnesol to control their shape, a process called morphogenesis. This study explores how Candida albicans and Saccharomyces cerevisiae use these signals competitively.
Area of Science:
- Microbiology
- Biochemistry
- Chemical Biology
Background:
- Yeast typically exist as unicellular organisms, but can transition to elongated hyphal structures.
- This morphological transition is regulated by quorum sensing molecules, with farnesol and tyrosol identified in Candida albicans.
- Aromatic alcohols, products of amino acid metabolism, are implicated in regulating morphogenesis in Saccharomyces cerevisiae.
Purpose of the Study:
- To investigate the role of quorum sensing and signalling molecules in yeast morphogenesis.
- To compare the mechanisms of morphological regulation in Candida albicans and Saccharomyces cerevisiae.
- To present evidence of competitive strategies employed by these yeasts using signalling molecules.
Main Methods:
- Analysis of quorum sensing and signalling molecules involved in yeast development.
- Comparative study of morphological regulation in Candida albicans and Saccharomyces cerevisiae.
- Investigation of competitive interactions mediated by chemical signals.
Main Results:
- Farnesol and tyrosol are key quorum sensing molecules in Candida albicans, influencing morphogenesis.
- Various signalling molecules like isoamyl alcohol and E-nerolidol also regulate C. albicans development.
- Evidence suggests Saccharomyces cerevisiae utilizes aromatic alcohols for similar regulatory purposes, though mechanisms differ.
- The study provides examples of competitive strategies utilized by C. albicans and S. cerevisiae.
Conclusions:
- Quorum sensing and signalling molecules play a crucial role in regulating yeast morphogenesis.
- Distinct yet comparable mechanisms of morphological control exist in C. albicans and S. cerevisiae.
- These signalling molecules contribute to competitive advantages for yeasts in microbial environments.
Keywords:
Candida albicansQuorum sensingalcohol dehydrogenasebiofilmsfusel alcoholssaccharomyces cerevisiaeMore Related Videos
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