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Updated: Nov 16, 2025

Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2
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Cardiovascular Disease Risk and Outcomes in Patients Infected With SARS-CoV-2

Diana Espinoza1, Manasa Jasti1, Umme Haani Malwi1

  • 1Internal Medicine, MacNeal Hospital, Berwyn, USA.

Cureus
|February 25, 2021
PubMed

Insights

Coronavirus disease 2019 (COVID-19) can cause serious cardiovascular complications, increasing mortality risk. Understanding this link is crucial for managing patients and improving their prognosis.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Internal Medicine

Background:

  • Cardiovascular involvement is a significant complication of coronavirus disease 2019 (COVID-19).
  • Cardiac complications are associated with increased mortality in COVID-19 patients.
  • The interplay between COVID-19 and cardiovascular health necessitates close clinical observation.

Observation:

  • This study presents three cases of patients with COVID-19.
  • Baseline cardiac risk factors were recorded for each patient.
  • Cardiac complications arising during COVID-19 infection were documented.

Findings:

  • The three patients experienced varying cardiac complications post-COVID-19 infection.
  • Outcomes differed among the patients, influenced by their cardiac status and COVID-19 severity.
  • The case series highlights the diverse cardiovascular manifestations of COVID-19.

Implications:

  • Physicians must closely monitor cardiovascular health in COVID-19 patients.
  • Recognizing cardiac complications can improve patient management strategies.
  • Understanding the association aids in predicting prognosis for COVID-19 patients with cardiac involvement.

Keywords:
cardiac compromisecardiovascularchest paincovid-19inflammationmortalitymyocarditisrisk factorssyncopetroponin

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