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Cinnamon effects on blood pressure and metabolic profile: A double-blind, randomized, placebo-controlled trial in

Fatemeh Shirzad1,2, Negar Morovatdar3,2, Ramin Rezaee3,4

  • 1Department of Cardiology, Emam Reza Educational Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Avicenna Journal of Phytomedicine
|February 25, 2021
PubMed

Insights

This pilot study found that cinnamon moderately reduced systolic blood pressure and improved lipid profiles in patients with stage 1 hypertension. Cinnamon may serve as a complementary treatment for hypertension, offering benefits for blood pressure and cholesterol levels.

Area of Science:

  • Cardiovascular Medicine
  • Metabolic Health
  • Clinical Nutrition

Background:

  • Blood pressure management in stage 1 hypertension (S1HTN) is crucial.
  • The effect of cinnamon on blood pressure and metabolic parameters is debated.
  • This study investigates cinnamon's impact on S1HTN patients.

Purpose of the Study:

  • To assess the effect of cinnamon on blood pressure in S1HTN patients.
  • To evaluate cinnamon's impact on the metabolic profile, including lipids and fasting blood sugar.
  • To provide evidence for cinnamon as a potential complementary therapy.

Main Methods:

  • A double-blind, placebo-controlled, randomized trial was conducted over 90 days.
  • Participants (S1HTN) received either 1500 mg/day cinnamon or a placebo.
  • 24-hour ambulatory blood pressure monitoring (ABPM), lipid profiles, and fasting blood sugar were measured at baseline and day 90.

Main Results:

  • Cinnamon significantly decreased mean 24-hour and daytime systolic blood pressure (SBP).
  • A significant increase in HDL-c and decrease in LDL-c was observed in the cinnamon group.
  • Fasting blood sugar remained unchanged, while lipid profiles showed significant improvement with cinnamon.

Conclusions:

  • Cinnamon demonstrated a statistically significant, though moderate, reduction in ambulatory SBP.
  • Significant improvements in lipid profiles were observed with cinnamon supplementation.
  • Cinnamon may be considered a beneficial complementary treatment for individuals with stage 1 hypertension.
Abstract

Keywords:
CholesterolCinnamonHDLHypertensionLDL

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