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Author Spotlight: Generating Neuronal Phenotypic Profiles - A Protocol to Culture and Image Human Midbrain Dopaminergic Neurons
Published on: July 7, 2023
Open science takes on Parkinson's disease
Ekemini Au Riley1, Randy Schekman1,2
1Aligning Science Across Parkinson's (ASAP), Chevy Chase, United States.
Abstract:
The Aligning Science Across Parkinson's (ASAP) initiative was set up to improve understanding of the biology underlying the onset and progression of Parkinson's disease. With an emphasis on open science and collaboration, we have assembled a research network led by nearly 100 investigators to explore the pathology of Parkinson's disease, and this network will soon expand to include researchers working on relevant (dys)-functional neural circuits. We have also contributed to large-scale genetics and patient cohort initiatives related to the disease. We hope that these actions, and others planned for the future, will deepen our knowledge of the molecular mechanisms underlying the origin and evolution of Parkinson's disease and, ultimately, contribute to the development of novel therapies.
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