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Revolutionizing Medical Data Sharing Using Advanced Privacy-Enhancing Technologies: Technical, Legal, and Ethical

James Scheibner1,2, Jean Louis Raisaro3,4, Juan Ramón Troncoso-Pastoriza5

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Multiparty homomorphic encryption enhances medical data sharing privacy and utility. This advanced technology, combining homomorphic encryption and secure multiparty computation, offers a legally compliant, efficient alternative to traditional data sharing contracts.

Keywords:
GDPRGeneral Data Protection RegulationInteroperabilityanonymizationcentralized approachdata governancedata privacydata protectiondata sharingdecentralized approachencryptionethicsfederated approachpatient data privacyprivacypseudonymizationresearch

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Area of Science:

  • Medical Informatics
  • Cryptography
  • Data Privacy

Background:

  • Multisite medical data sharing is essential for clinical practice and research.
  • Current privacy-enhancing technologies and data sharing contracts present inefficiencies and privacy concerns.
  • Existing methods often lead to lengthy administrative processes, hindering medical research and treatment.

Purpose of the Study:

  • To present a synthesis of homomorphic encryption and secure multiparty computation, termed multiparty homomorphic encryption (MHE).
  • To demonstrate how MHE provides a mathematical guarantee of privacy while improving performance over individual methods.
  • To argue that MHE meets the General Data Protection Regulation (GDPR) requirements for anonymized medical data sharing.

Main Methods:

  • Integration of homomorphic encryption (HE) and secure multiparty computation (SMC) into a unified framework.
  • Mathematical analysis of privacy guarantees offered by the combined MHE approach.
  • Evaluation of MHE's performance advantages compared to standalone HE or SMC.

Main Results:

  • MHE offers a superior performance profile compared to using HE or SMC independently.
  • Data processed and shared via MHE can be considered anonymized under GDPR.
  • MHE significantly reduces the need for bespoke data sharing contracts between institutions.

Conclusions:

  • Multiparty homomorphic encryption presents a robust solution for secure and efficient multisite medical data sharing.
  • This technology aligns with stringent data protection regulations like GDPR, facilitating anonymized data exchange.
  • Adoption of MHE can accelerate medical research and encourage the use of common data interoperability standards.