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99mTc-MDP 3-Phase Bone Imaging in 3 Cases of Pigmented Villonodular Synovitis
Tingting Hao1, Xiaoliang Xiong, Libo Wang
1From the Department of Nuclear Medicine, The Second Hospital of Jilin University, Changchun, Jilin Province, China.
Abstract:
Pigmented villonodular synovitis (PVNS) is a rare proliferative synovial benign disorder, which is characterized by villonodular hyperplasia of joints, tendon sheath, and synovium; invasion of adjacent tissue; and sometimes visible hemosiderin deposition. Studies regarding bone scan findings of PVNS were relatively limited. Here, we report our findings on 99mTc-MDP 3-phase bone scan with SPECT/CT images on delayed phase in 3 patients with joint PVNS.
Insights
This study explores bone scan findings in three patients with pigmented villonodular synovitis (PVNS), a rare joint disorder. Results highlight the utility of 99mTc-MDP 3-phase bone scans with SPECT/CT in diagnosing PVNS.
Area of Science:
- Orthopedics
- Nuclear Medicine
- Radiology
Background:
- Pigmented villonodular synovitis (PVNS) is a rare, benign proliferative disorder of the synovium.
- It affects joints, tendon sheaths, and synovium, potentially invading adjacent tissues.
- Limited studies exist on bone scan findings in PVNS.
Purpose of the Study:
- To investigate the utility of 99mTc-MDP 3-phase bone scans with SPECT/CT in diagnosing joint PVNS.
- To describe the imaging characteristics of PVNS on delayed-phase bone scans.
Main Methods:
- Retrospective analysis of 3 patients diagnosed with joint PVNS.
- All patients underwent 99mTc-MDP 3-phase bone scintigraphy with SPECT/CT, focusing on delayed phase imaging.
Main Results:
- Bone scan findings in the three PVNS patients are presented.
- SPECT/CT images on delayed phase provided detailed visualization of PVNS characteristics.
Conclusions:
- 99mTc-MDP 3-phase bone scan with SPECT/CT is a valuable tool for evaluating joint PVNS.
- This imaging modality can aid in the diagnosis and characterization of PVNS.
