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Impact of cancer evolution on immune surveillance and checkpoint inhibitor response

Yin Wu1, Dhruva Biswas2, Charles Swanton3

  • 1Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, NW1 1AT, UK; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, Paul O'Gorman Building, London, WC1E 6DD, UK; Peter Gorer Department of Immunobiology, School of Immunology & Microbial Sciences, King's College London, London, SE1 9RT, UK.

Seminars in Cancer Biology
|February 25, 2021
PubMed

Keywords:
Genomic instabilityImmune checkpoint inhibitorsImmune surveillanceIntratumour heterogeneityNeoantigens

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