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Related Concept Videos

Neuroplasticity01:01

Neuroplasticity

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Neuroplasticity reflects the brain's remarkable capacity to adapt and evolve, responding dynamically to learning, experiences, or injury by reorganizing its neural circuitry. This reorganization involves creating new neural connections and refining old ones through a series of biological processes that contribute to the brain's lifelong development and adaptability.
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Plasticity00:58

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Plasticity is the property where an object loses its elasticity and undergoes irreversible deformation, even after the deformation forces are eliminated. If a material deforms irreversibly without increasing stress or load, then this is called ideal plasticity. For example, when a force is applied to an aluminum rod, it changes its shape, but it does not return to its original shape once the force is removed. Plastic deformation or ductility is thus a permanent deformation or change in the...
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Long-term Potentiation01:25

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Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
Hebbian LTP
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Long-term Potentiation01:35

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Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre- and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
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Instinctive Drift01:05

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Instinctive drift refers to the tendency of animals to revert to their innate behaviors despite repeated reinforcement. Breland and Breland demonstrated this concept in an experiment with a raccoon. The raccoon was trained to pick up two coins and place them in a container in exchange for food. Initially, the raccoon learned to associate the coins with food, making them a conditioned stimulus or a substitute for food. However, over time, the raccoon became less willing to put the coins into the...
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Higher Mental Functions of Brain: Learning and Memory01:26

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Memory is one of the most vital higher mental functions of the brain. Memory is closely related to learning because it enables us to retain information and experiences from our past to use them in our present life. It also helps us to remember facts, events, and skills, such as riding a bike or swimming. There are two types of memory — declarative memory, which involves memorizing facts or events, and procedural memory, which enables us to remember how to do something like writing or...
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Related Experiment Video

Updated: Nov 16, 2025

A Lightweight, Headphones-based System for Manipulating Auditory Feedback in Songbirds
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A Lightweight, Headphones-based System for Manipulating Auditory Feedback in Songbirds

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Intrinsic plasticity and birdsong learning.

Arij Daou1, Daniel Margoliash1

  • 1University of Chicago, United States.

Neurobiology of Learning and Memory
|February 25, 2021
PubMed
Summary
This summary is machine-generated.

Neural intrinsic plasticity, distinct from synaptic plasticity, plays a key role in learning. This study reveals how intrinsic neuronal properties in zebra finches dynamically change to support learned song development and adaptation.

Keywords:
Auditory feedbackDevelopmentHomeostatic plasticityIntrinsic excitationIntrinsic propertiesSongbirdsZebra finch

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Area of Science:

  • Neuroscience
  • Computational Neuroscience
  • Animal Behavior

Background:

  • Synaptic plasticity is the primary mechanism for brain information processing and storage.
  • Intrinsic plasticity, a non-synaptic mechanism, is increasingly recognized but its role in learning is unclear.
  • Understanding intrinsic plasticity is crucial for a comprehensive view of neural computation.

Purpose of the Study:

  • To investigate the role of intrinsic excitability plasticity in learned birdsong.
  • To examine how intrinsic neuronal properties in zebra finches relate to song learning and development.
  • To explore the dynamic changes in intrinsic properties in response to auditory feedback.

Main Methods:

  • Focused on basal-ganglia projecting song system neurons in zebra finches.
  • Analyzed the relationship between intrinsic neuronal properties and learned song characteristics.
  • Investigated developmental changes and dynamic adjustments of intrinsic properties.

Main Results:

  • Intrinsic properties of song neurons are linked to individual learned songs in zebra finches.
  • These intrinsic properties exhibit developmental changes and dynamic modulation based on auditory feedback.
  • Intrinsic plasticity offers computational advantages distinct from synaptic plasticity.

Conclusions:

  • Intrinsic plasticity is a significant mechanism in birdsong learning and adaptation.
  • Reciprocal interactions between intrinsic and network properties are key to understanding song learning.
  • Further research into intrinsic plasticity will illuminate brain learning mechanisms.