Indications and contra-indications for perforation keratoplasty

Thirty years' experience with perforating keratoplasty has shown us new indications for this technique, but certainly also new contra-indications. At first the prognosis of perforating keratoplasty improved because of better surgical techniques, so that the number of indications increased. Recently a better prognosis for heavily vascularized eyes has become possible thanks to HLA-matched donor material.