Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

127
DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
127
Computed Tomography01:10

Computed Tomography

7.6K
Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
7.6K
Imaging Studies I: CT and MRI01:14

Imaging Studies I: CT and MRI

588
Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
588
Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

319
Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
319
Positron Emission Tomography01:29

Positron Emission Tomography

6.5K
Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
6.5K
Imaging Studies IV: Magnetic Resonance Imaging01:27

Imaging Studies IV: Magnetic Resonance Imaging

122
Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...
122

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Synthesis of Nitazoxanide Derivatives as Potent and Orally Available HBx-DDB1 Inhibitors against Hepatitis B Virus.

ACS medicinal chemistry letters·2026
Same author

JPEG-aware steganalysis: explicit frequency modeling with dequantized DCT for real-world JPEG images.

Scientific reports·2026
Same author

Development and Biological Evaluation of a GLUT-Inhibiting Theranostic Agent, MF48, for Colorectal Cancer Therapy.

ACS applied bio materials·2026
Same author

Commentary: Modulation of ASC-derived extracellular vesicles containing cargo that specifically enhances wound healing.

Frontiers in pharmacology·2026
Same author

Evaluating sleep quality in a non-intrusive manner using contactless ballistocardiography and audio signals through a LSTM-TCN machine learning model.

Frontiers in network physiology·2026
Same author

Integrated catalyst-transport nickel-iron porous electrode for anion exchange membrane water electrolysis.

Nature communications·2026

Related Experiment Video

Updated: Nov 16, 2025

Four-Dimensional CT Analysis Using Sequential 3D-3D Registration
05:05

Four-Dimensional CT Analysis Using Sequential 3D-3D Registration

Published on: November 23, 2019

8.3K

Four-dimensional inverse-geometry computed tomography: a preliminary study.

Kyeong-Hyeon Kim1,2, Dong-Seok Shin1,2, Sang-Won Kang1,2

  • 1Department of Biomedical Engineering, Department of Biomedicine and Health Sciences, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

Physics in Medicine and Biology
|February 25, 2021
PubMed
Summary

This study introduces respiratory-correlated four-dimensional (4D) inverse geometry computed tomography (IGCT), demonstrating superior image quality compared to conventional cone-beam computed tomography (CBCT). The novel 4D IGCT method reduces artifacts and improves image stability across respiratory phases.

More Related Videos

Four-Dimensional Computed Tomography-Guided Valve Sizing for Transcatheter Pulmonary Valve Replacement
09:57

Four-Dimensional Computed Tomography-Guided Valve Sizing for Transcatheter Pulmonary Valve Replacement

Published on: January 20, 2022

2.9K
High Resolution 3D Imaging of Ex-Vivo Biological Samples by Micro CT
08:57

High Resolution 3D Imaging of Ex-Vivo Biological Samples by Micro CT

Published on: June 21, 2011

19.0K

Related Experiment Videos

Last Updated: Nov 16, 2025

Four-Dimensional CT Analysis Using Sequential 3D-3D Registration
05:05

Four-Dimensional CT Analysis Using Sequential 3D-3D Registration

Published on: November 23, 2019

8.3K
Four-Dimensional Computed Tomography-Guided Valve Sizing for Transcatheter Pulmonary Valve Replacement
09:57

Four-Dimensional Computed Tomography-Guided Valve Sizing for Transcatheter Pulmonary Valve Replacement

Published on: January 20, 2022

2.9K
High Resolution 3D Imaging of Ex-Vivo Biological Samples by Micro CT
08:57

High Resolution 3D Imaging of Ex-Vivo Biological Samples by Micro CT

Published on: June 21, 2011

19.0K

Area of Science:

  • Medical Imaging
  • Computed Tomography
  • Image Reconstruction

Background:

  • Respiratory motion significantly degrades image quality in computed tomography (CT).
  • Conventional cone-beam computed tomography (CBCT) struggles to accurately reconstruct dynamic anatomical regions.
  • Four-dimensional (4D) imaging techniques are crucial for motion-compensated CT reconstruction.

Purpose of the Study:

  • To introduce and evaluate a novel respiratory-correlated four-dimensional (4D) inverse geometry computed tomography (IGCT) system.
  • To compare the image quality of 4D IGCT against conventional CBCT using virtual phantoms.
  • To assess the impact of acquisition parameters on 4D IGCT performance.

Main Methods:

  • Acquired projection data using IGCT in a single gantry rotation (120 s).
  • Utilized static Defrise, 4D Shepp-Logan, and 4D XCAT virtual phantoms.
  • Performed phase-based sorting and rebinning, followed by Feldkamp-Davis-Kress reconstruction at each phase.

Main Results:

  • 4D IGCT demonstrated reduced cone-beam artifacts and uniform vertical profiles compared to CBCT.
  • Higher structural similarity index measure (SSIM) and lower root mean square error (RMSE) for 4D IGCT (e.g., SSIM: 0.899 vs. 0.784 for Shepp-Logan).
  • Improved image stability across respiratory phases for 4D IGCT, unlike CBCT.

Conclusions:

  • The proposed 4D IGCT system offers superior image quality over conventional CBCT.
  • Accurate acquisition parameter selection is critical for optimal 4D IGCT performance.
  • 4D IGCT shows significant potential for improved motion-compensated CT imaging.