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Updated: Nov 16, 2025

Corneal Donor Tissue Preparation for Endothelial Keratoplasty
Published on: June 12, 2012
A Case of Paracentral Corneal Perforation Treated with One-Bite Mini-Keratoplasty
Yoshitake Kato1, Daisuke Nagasato1, Shunsuke Nakakura1
1Saneikai Tsukazaki Hospital, Department of Ophthalmology, Himeji, Japan.
Abstract:
A 61-year-old man presented with corneal perforation of 1.0 mm in diameter in his right eye caused by a metallic foreign body fragment. We used the "one-bite mini-keratoplasty" technique, which uses a cornea patch with a single host-graft-host suture to stop aqueous humor leakage. Postoperatively, the graft was completely epithelialized. The suture was removed and the use of soft contact lens was discontinued. Postoperative best-corrected visual acuity (BCVA) recovered to 180/200 and corneal astigmatism was 0.6 diopters. The postoperative course was unremarkable, but corneal perforation recurred due to an ocular contusion at 17 months. He was reoperated using the same technique. His BCVA was 160/200 and corneal astigmatism was 1.1 diopters after reoperation. Despite performing this surgical technique twice for corneal perforation, optimal visual function was maintained even after 2 years. For paracentral corneal perforations, our simple technique may reduce astigmatism and maintain high visual function.

