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Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries
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Longitudinal caries prevalence in a comprehensive, multicomponent, school-based prevention program.

Jacqueline R Starr, Ryan R Ruff, Joseph Palmisano

    Journal of the American Dental Association (1939)
    |February 26, 2021
    PubMed
    Summary
    This summary is machine-generated.

    A school-based, aerosol-free dental program significantly reduced children's cavities by over 50%. This comprehensive approach, including sealants and fluoride, shows promise for widespread caries prevention in schools.

    Keywords:
    Caries preventionaerosol-freecommunity-based care

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    Area of Science:

    • Pediatric Dentistry
    • Public Health Interventions
    • Dental Caries Prevention

    Background:

    • Global children's caries prevalence remains high (>30%) with little change over 30 years.
    • School-based programs offer effective, accessible, and aerosol-free interventions for dental caries.
    • Barriers to traditional dental care can be overcome through school-based initiatives.

    Purpose of the Study:

    • To evaluate the clinical effectiveness of a comprehensive, aerosol-free, school-based caries prevention program.
    • To assess the impact of the program on the prevalence of untreated caries in elementary school children.

    Main Methods:

    • A 6-year prospective open cohort study involving 6,927 children across 33 US public elementary schools.
    • Interventions included prophylaxis, glass ionomer sealants and restorations, fluoride varnish, hygiene products, and education.
    • Generalized estimating equations were used to analyze changes in untreated caries prevalence over time.

    Main Results:

    • The prevalence of untreated caries decreased by over 50% in both study phases.
    • Phase 1 saw a reduction from 39% to 18%, and Phase 2 from 28% to 10%.
    • The adjusted odds ratio for untreated caries per visit was 0.79 (95% CI, 0.73–0.85).

    Conclusions:

    • The school-based program demonstrated substantial reductions in children's untreated caries.
    • This supports the expansion of traditional dental practices to include community- and school-based aerosol-free care.
    • Comprehensive school-based interventions are effective in preventing dental caries in children.