Related Experiment Video
Updated: Nov 16, 2025

Use of a Low-flow Digital Anesthesia System for Mice and Rats
Published on: September 7, 2016
The effect of low flow anesthesia on hemodynamic and peripheral oxygenation parameters in obesity surgery
Mesut Öterkuş1, İlksen Dönmez1, Aysu H Nadir1
1From the Department of Anesthesiology and Reanimation (Öterkuş), Faculty of Medicine, Malatya Turgut Özal University, Malatya; from the Department of Anesthesiology and Reanimation (Dönmez), Beyoglu Eye Training and Research Hospital, İstanbul; from the Department of Anesthesiology and Reanimation (Nadir), Izmir Katip Celebi University Ataturk Training and Research Hospital, İzmir; and from the Department of Cardiology (Rencüzoğulları, Karabağ), Department of General Surgery (Binnetoğlu), Medical Faculty, Kafkas University, Kars, Turkey.
Objectives:
To investigate the effects of low-flow anesthesia on hemodynamic parameters and recovery from anesthesia in obese individuals undergoing laparoscopic surgery.
Methods:
This randomized-controlled and prospective study included 44 obese patients who underwent laparoscopic sleeve gastrectomy operation. The patients were randomly allocated into 2 groups as low-flow and high-flow anesthesia. Further, the groups compared in terms of hemodynamic parameters, anesthesia recovery times, operation times, and arterial blood gas parameters.
Results:
The groups were similar with respect to demographic data. Heart rate, peripheral oxygen saturation, arterial blood pressure measurements, end-tidal, and CO2, lactate levels measurements were similar in both groups during the entire procedure. There was also no statistically significant difference in terms of arterial blood gas parameters or anesthesia recovery periods.
Conclusion:
Low-flow anesthesia in laparoscopic obesity surgery seems to be safer compared to high-flow anesthesia in terms of the adequacy of tissue perfusion, depth of anesthesia, and postoperative recovery.
Related Concept Videos
General Anesthesia: Overview
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
Drug Dosing: Obese Patients
Pharmacokinetics in Obese Patients: Drug Absorption and Distribution
Cardiomyopathy VII: Pre and Post Operative Nursing Management
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion

