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[Efficacy of Tranexamic Acid to decrease perioperative bleeding in primary total reverse arthroplasty].

R B Palmieri-Bouchan1, V H Aguirre-Rodríguez1, L E Salinas-Vela1

  • 1Alta Especialidad en Cirugía de Reconstrucción Articular de Hombro y Codo. Facultad Mexicana de Medicina de la Universidad La Salle. Hospital Ángeles Pedregal, GASS. México.

Acta Ortopedica Mexicana
|February 26, 2021
PubMed
Summary
This summary is machine-generated.

Tranexamic acid (ATXM) may reduce blood loss and transfusion needs in reverse shoulder arthroplasty. This study found a tendency for less bleeding and significantly lower blood product use in patients receiving ATXM.

Keywords:
Tranexamic acidbleedingcomplicationsreverse replacementshoulder

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Area of Science:

  • Orthopedic Surgery
  • Anesthesiology
  • Hematology

Background:

  • Reverse shoulder arthroplasty is effective for osteoarthritis and rotator cuff deficiency but risks significant blood loss and hematoma.
  • Managing perioperative bleeding is crucial for patient safety and surgical outcomes.

Purpose of the Study:

  • To evaluate the effectiveness of tranexamic acid (ATXM) in minimizing perioperative bleeding during primary reverse shoulder arthroplasty.

Main Methods:

  • A cohort of 31 patients undergoing primary reverse arthroplasty was divided into two groups.
  • Group A (17 patients) received 1g IV tranexamic acid preoperatively; Group B (14 patients) did not.
  • Blood loss, hemoglobin/hematocrit changes, and transfusion requirements were measured and compared.

Main Results:

  • While not statistically significant, there was a trend towards reduced bleeding in surgical drainage (115.6ml vs. 162.65ml) and smaller decreases in hemoglobin and hematocrit in the ATXM group.
  • A significant reduction in the need for blood product transfusion was observed in patients who received ATXM (p=0.0441).

Conclusions:

  • Tranexamic acid (ATXM) shows a trend towards reducing postoperative bleeding in reverse shoulder arthroplasty.
  • ATXM significantly decreases the requirement for blood transfusions in these patients.