Related Experiment Video
Updated: Nov 16, 2025

Assessing Therapeutic Angiogenesis in a Murine Model of Hindlimb Ischemia
Published on: June 8, 2019
Repeat BTK revascularization: when, how and what are the results?
Sabine Steiner1, Andrej Schmidt2
1Division of Angiology, Department of Internal Medicine, Neurology and Dermatology, University Hospital Leipzig, Leipzig, Germany - Sabine.steiner@medizin.uni-leipzig.de.
Repeat below-the-knee (BTK) endovascular interventions are necessary due to high re-stenosis rates after initial procedures. This review examines the need, options, and outcomes for repeat BTK interventions in chronic limb-threatening ischemia patients.
Area of Science:
- Vascular Surgery
- Interventional Cardiology
- Endovascular Interventions
Background:
- Increasing prevalence of chronic limb-threatening ischemia (CLTI) due to aging populations and diabetes.
- Below-the-knee (BTK) lesions are common in CLTI, requiring complex revascularization.
- Advances in endovascular techniques and devices have improved short-term outcomes for BTK interventions.
Purpose of the Study:
- To summarize current knowledge on repeat BTK interventions for CLTI.
- To review the indications, available options, and outcomes of repeat BTK procedures.
- To present data on repeat interventions in complex peripheral arterial occlusive disease.
Main Methods:
- Limited literature review of MEDLINE, EMBASE, and conference proceedings.
- Keywords included "angioplasty," "endovascular intervention," "infrapopliteal," "tibial arteries," and "below the knee."
- Search focused on English-language publications from 2000 to 2020.
Main Results:
- High rates of re-stenosis and re-occlusion are observed after initial infrapopliteal interventions.
- These high rates limit the long-term success of primary procedures.
- Frequent repeat interventions are often necessary to maintain patency and limb salvage.
Conclusions:
- Repeat BTK interventions are crucial for managing CLTI patients with recurrent disease.
- Understanding the need, options, and outcomes of repeat procedures is essential for optimizing patient care.
- Further research and data presentation are needed to refine strategies for repeat BTK interventions.
More Related Videos
Related Concept Videos
Peripheral Artery Disease V: Postoperative Nursing Management
Peripheral Artery Disease III: Interprofessional Care
Varicose Veins II: Diagnostic Studies and Interprofessional Care
Venous Thrombosis III: Interprofessional Care

