Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Chemotaxis in E. coli01:27

Chemotaxis in E. coli

367
Chemotaxis in Escherichia coli is a sensory-driven motility mechanism that enables bacteria to navigate chemical gradients, moving toward beneficial environments while avoiding harmful conditions. This process relies on a signal transduction system integrating external chemical cues with flagellar motor control.Chemoreceptors and Signal DetectionE. coli detects chemical gradients through methyl-accepting chemotaxis proteins (MCPs), which are membrane-bound chemoreceptors that sense attractants...
367
Flagella and Motility in Bacteria01:18

Flagella and Motility in Bacteria

1.4K
Flagella are specialized, thread-like structures that extend from a bacteria's cell envelope. They play a crucial role in motility and chemotaxis. Their structural organization and functioning exemplify sophisticated biological engineering, enabling bacterial survival and adaptability in diverse environments.Structure of the FlagellumA bacterial flagellum consists of three key components: the filament, the hook, and basal body. The filament, a long, helical structure composed of repeating...
1.4K
Bacterial Signaling01:30

Bacterial Signaling

38.5K
Bacterial signaling can occur within bacteria (intracellular) or between bacteria (intercellular). At times, a group of bacteria behaves like a community. To achieve this, they engage in quorum sensing, the perception of higher cell density that causes changes in gene expression. Quorum sensing involves both extracellular and intracellular signaling. The signaling cascade starts with a molecule called an autoinducer (AI). Individual bacteria produce AIs that move out of the bacterial cell...
38.5K
Enteric Nervous System: Regulation of GI Motor Activity01:11

Enteric Nervous System: Regulation of GI Motor Activity

1.2K
The Enteric Nervous System (ENS) plays a pivotal role in regulating gastrointestinal or GI motor activity. This complex network of nerves, deeply embedded within the gut wall, responds to changes in the gut environment and receives input from both the autonomic nervous system and the central nervous system. By doing so, the ENS operates various programs tailored to the body's nutritional status and needs.
During periods of fasting, the ENS initiates the migrating myoelectric complex, a...
1.2K
Gene Regulation in Microbial Communities: Quorum Sensing01:28

Gene Regulation in Microbial Communities: Quorum Sensing

229
Quorum sensing is a mechanism of bacterial communication that enables coordinated gene expression in response to changes in population density. This facilitates collective behaviors that enhance survival, resource acquisition, and ecological adaptation. This process relies on small signaling molecules called autoinducers that accumulate as bacterial populations grow. When a critical threshold concentration of autoinducers is reached, bacterial cells collectively modify gene expression,...
229
Cell Motility through Blebbing01:16

Cell Motility through Blebbing

2.2K
Blebs are a type of membrane protrusion formed by the internal hydrostatic pressure of the cytoplasm. Blebs are observed in several cell types, including fibroblasts, immune cells, and single-celled organisms like the amoeba. The primary function of blebs is cell locomotion and apoptosis, but they are also found during necrosis and cell division. The life cycle of a bleb comprises an initiation phase followed by the expansion and retraction phases.
Blebbing Through the Matrix
In multicellular...
2.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Social isolation during adolescence alters novel object recognition memory, brain and gut gene expression, and microbiota composition in a sex-specific manner.

Brain, behavior, & immunity - health·2026
Same author

Spinal afferent endings in the gastrointestinal tract.

Autonomic neuroscience : basic & clinical·2026
Same author

Different types of sensory nerve endings in the urinary bladder of mice arising from dorsal root ganglia (DRG) at the thoracolumbar region of vertebral column.

Cell and tissue research·2026
Same author

Combined peripheral cannabinoid CB1 and CB2 receptor activation abolishes cystitis-induced bladder hyperalgesia.

Autonomic neuroscience : basic & clinical·2026
Same author

How changes in salinity modify patterns of gastrointestinal motility in the intestine of freshwater barramundi.

Autonomic neuroscience : basic & clinical·2026
Same author

Esophageal peristalsis in health and disease: mechanistic insights.

Physiological reviews·2026

Related Experiment Video

Updated: Nov 16, 2025

Video Imaging and Spatiotemporal Maps to Analyze Gastrointestinal Motility in Mice
07:41

Video Imaging and Spatiotemporal Maps to Analyze Gastrointestinal Motility in Mice

Published on: February 3, 2016

14.4K

Microbial signalling in colonic motility.

Julie E Dalziel1, Nick J Spencer2, Wayne Young1

  • 1Smart Foods Innovation Centre of Excellence, AgResearch, Palmerston North, New Zealand.

The International Journal of Biochemistry & Cell Biology
|February 26, 2021
PubMed
Summary

Bacterial microvesicles may act as messengers, communicating between gut microbes and the enteric nervous system (ENS). This interaction influences intestinal motility and microbial balance.

Keywords:
BacteriaColonLipopolysaccharideMicrovesicleProbiotic

More Related Videos

Gastrointestinal Motility Monitor GIMM
08:15

Gastrointestinal Motility Monitor GIMM

Published on: December 1, 2010

31.2K
Spatiotemporal Mapping of Motility in Ex Vivo Preparations of the Intestines
12:00

Spatiotemporal Mapping of Motility in Ex Vivo Preparations of the Intestines

Published on: January 27, 2016

10.6K

Related Experiment Videos

Last Updated: Nov 16, 2025

Video Imaging and Spatiotemporal Maps to Analyze Gastrointestinal Motility in Mice
07:41

Video Imaging and Spatiotemporal Maps to Analyze Gastrointestinal Motility in Mice

Published on: February 3, 2016

14.4K
Gastrointestinal Motility Monitor GIMM
08:15

Gastrointestinal Motility Monitor GIMM

Published on: December 1, 2010

31.2K
Spatiotemporal Mapping of Motility in Ex Vivo Preparations of the Intestines
12:00

Spatiotemporal Mapping of Motility in Ex Vivo Preparations of the Intestines

Published on: January 27, 2016

10.6K

Area of Science:

  • Gastroenterology
  • Microbiology
  • Neuroscience

Background:

  • Sensory nerve endings in the GI tract respond to bacterial signals, influencing motility and homeostasis.
  • Enteric neurons and smooth muscle cells possess receptors for bacterial substances like SCFAs, bile acids, and LPS.
  • Bacterial signaling is crucial for gut function, but the mechanisms of interaction are still being uncovered.

Purpose of the Study:

  • To explore the role of bacterial microvesicles in mediating communication between the gut microbiota and the host.
  • To investigate if bacterial microvesicles can cross the gut barrier and influence enteric nervous system (ENS) function.

Main Methods:

  • Review of recent studies on bacterial signaling and gut-host interactions.
  • Analysis of the potential for bacterial microvesicles to act as intercellular communicators.
  • Exploration of the implications for intestinal motility and microbial homeostasis.

Main Results:

  • Bacterial microvesicles have been shown to cross the gut epithelial barrier.
  • These microvesicles may affect intestinal motility, suggesting a role in host-microbe communication.
  • Bacterial microvesicles could serve as a delivery system for signals between microbes and the host.

Conclusions:

  • Bacterial microvesicles represent a novel pathway for communication between the gut microbiota and the enteric nervous system.
  • This intercellular communication mechanism may play a significant role in regulating intestinal motility and maintaining microbial homeostasis.
  • Further research into bacterial microvesicles could reveal new therapeutic targets for gastrointestinal disorders.