Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Analgesia and Pain Management01:25

Analgesia and Pain Management

1.1K
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
1.1K
Methods of Documentation VI: Case Management Model01:15

Methods of Documentation VI: Case Management Model

722
The case management model is a multidisciplinary approach that involves healthcare professionals from diverse disciplines, such as physicians, nurses, therapists, social workers, and pharmacists, working collaboratively to address the various needs of patients. Each healthcare professional brings unique expertise and perspectives, contributing to a more comprehensive understanding of the patient's condition and tailoring treatment plans accordingly.
For example, a patient with a chronic...
722
Pain01:20

Pain

1.0K
Pain serves as a critical warning signal that alerts the body to potential or actual harm. When mechanical pressure on the skin is intense, such as from a sharp pinch, the sensation transitions from touch to pain. Similarly, extreme temperatures, like a hot pot handle, convert the sensation of heat into pain. Pain can also result from overstimulation of other senses, such as blinding light, loud noise, or the intense heat from habañero peppers. This ability to sense pain is essential for...
1.0K
Nociception01:44

Nociception

32.2K
Nociception—the ability to feel pain—is essential for an organism’s survival and overall well-being. Noxious stimuli such as piercing pain from a sharp object, heat from an open flame, or contact with corrosive chemicals are first detected by sensory receptors, called nociceptors, located on nerve endings. Nociceptors express ion channels that convert noxious stimuli into electrical signals. When these signals reach the brain via sensory neurons, they are perceived as pain.
32.2K
Peripheral Artery Disease IV: Nursing Management01:26

Peripheral Artery Disease IV: Nursing Management

146
 The nursing management of a patient with peripheral artery disease (PAD) begins with a thorough assessment of the patient’s health history and clinical manifestations.AssessmentHealth History: Evaluate the patient’s history of hypertension, hyperlipidemia, family history of cardiovascular issues, and lifestyle factors such as dietary patterns, smoking, and physical activity.Physical Examination:Assess the affected extremity for decreased or absent peripheral pulses,...
146
Chronic Pancreatitis II: Collaborative Care01:29

Chronic Pancreatitis II: Collaborative Care

173
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
173

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

CYP450-based reclassification of urinary metabolic ratio cutoffs for pain management and substance abuse treatment drugs.

Journal of opioid management·2026
Same author

Use of urinary metabolic ratio to detect possible deception in patients prescribed buprenorphine.

Journal of opioid management·2026
Same author

Analytical Performance of the Sixth Generation High-Sensitivity Cardiac Troponin T Assay.

The journal of applied laboratory medicine·2026
Same author

False positive urine drug screens.

Journal of analytical toxicology·2026
Same author

Comparison of six serum analyte workflows using routine liquid chromatography-tandem mass spectrometry methods at multiple laboratories with the Cobas i 601 analyzer, an automated mass spectrometry system.

Clinical chemistry and laboratory medicine·2026
Same author

Per Se Driving Under the Influence of Cannabis Statutes and Blood Delta-9-Tetrahydrocannabinol Concentrations following Short-Term Cannabis Abstinence.

Clinical chemistry·2025

Related Experiment Video

Updated: Nov 16, 2025

Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery
09:38

Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery

Published on: April 14, 2016

12.9K

Interpretation of Pain Management Testing Results Using Case Examples.

Philip M Sobolesky1, Breland E Smith1, Amadeo J Pesce2

  • 1Department of Pathology, Center for Advanced Laboratory Medicine, University of California, San Diego Health Systems, San Diego, CA.

The Journal of Applied Laboratory Medicine
|February 27, 2021
PubMed
Summary
This summary is machine-generated.

Interpreting urine drug tests is crucial for pain management. Understanding drug metabolism and immunoassay results aids in assessing patient compliance and detecting additional substances, especially with opiates and benzodiazepines.

More Related Videos

A Protocol of Manual Tests to Measure Sensation and Pain in Humans
07:28

A Protocol of Manual Tests to Measure Sensation and Pain in Humans

Published on: December 19, 2016

21.3K
Dynamic Quantitative Sensory Testing to Characterize Central Pain Processing
09:16

Dynamic Quantitative Sensory Testing to Characterize Central Pain Processing

Published on: February 16, 2017

17.3K

Related Experiment Videos

Last Updated: Nov 16, 2025

Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery
09:38

Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery

Published on: April 14, 2016

12.9K
A Protocol of Manual Tests to Measure Sensation and Pain in Humans
07:28

A Protocol of Manual Tests to Measure Sensation and Pain in Humans

Published on: December 19, 2016

21.3K
Dynamic Quantitative Sensory Testing to Characterize Central Pain Processing
09:16

Dynamic Quantitative Sensory Testing to Characterize Central Pain Processing

Published on: February 16, 2017

17.3K

Area of Science:

  • Clinical Chemistry
  • Pharmacology
  • Toxicology

Background:

  • Increasing opiate-related overdoses necessitate accurate clinical urine drug testing in pain management.
  • Interpreting urine drug test results requires understanding pharmacokinetics, metabolism, drug purity, and cutoff concentrations.

Purpose of the Study:

  • To provide examples for interpreting immunoassay and quantitative confirmatory urine drug testing results.
  • To emphasize the interpretation of opiate and benzodiazepine results due to their complex metabolic profiles.

Main Methods:

  • Case-based mini-review approach.
  • Analysis of immunoassay and quantitative confirmatory urine drug testing results.
  • Focus on opiate and benzodiazepine drug metabolism.

Main Results:

  • Interpretation of urine drug tests aids in determining patient medication compliance.
  • Identification of additional drugs in urine provides valuable clinical information.
  • Mass spectrometry is essential for specific drug identification and quantitative analysis.

Conclusions:

  • Accurate interpretation of urine drug tests supports effective pain management.
  • Understanding drug metabolism is key to interpreting complex drug profiles.
  • Quantitative mass spectrometry data is vital for assessing opiate medication compliance.