Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Combination Therapies and Personalized Medicine02:50

Combination Therapies and Personalized Medicine

5.6K
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
5.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Magnetic Resonance Imaging-Based Staging in Prostate Cancer-Are We Ready?

JAMA network open·2026
Same author

Development and validation of a quantitative ultra-performance liquid chromatography quadrupole time-of-flight method for urine organic acid analysis.

American journal of clinical pathology·2026
Same author

Should We Call Every Cancer a Rare Cancer?

Journal of clinical oncology : official journal of the American Society of Clinical Oncology·2026
Same author

Cross-assay RNA modeling reveals cancer biomarkers.

bioRxiv : the preprint server for biology·2026
Same author

On the predictability of progression-free survival in ovarian cancer from NanoString gene expression data.

bioRxiv : the preprint server for biology·2026
Same author

Copy Number-low/TP53-mutated Endometrial Cancer With Wild-type p53 Immunoexpression: Implications for Risk Stratification and Management When Using Next-generation Sequencing for Molecular Classification.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc·2026

Related Experiment Video

Updated: Nov 16, 2025

A Blood-based Test for the Detection of ROS1 and RET Fusion Transcripts from Circulating Ribonucleic Acid Using Digital Polymerase Chain Reaction
10:35

A Blood-based Test for the Detection of ROS1 and RET Fusion Transcripts from Circulating Ribonucleic Acid Using Digital Polymerase Chain Reaction

Published on: April 5, 2018

10.6K

Reengineering Critical Laboratory Testing for Timely Chemotherapeutic Management.

Xin Yi1, Edward Ki Yun Leung1, Diane Mika1

  • 1Department of Pathology, The University of Chicago, Chicago, IL.

The Journal of Applied Laboratory Medicine
|February 27, 2021
PubMed
Summary

Optimizing laboratory turnaround time (TAT) for chemotherapy patients significantly reduced testing times. Re-engineering workflows for complete blood count (CBC) and comprehensive metabolic panel (CMP) tests enabled faster chemotherapy delivery.

More Related Videos

Evaluating the Effectiveness of Cancer Drug Sensitization In Vitro and In Vivo
09:19

Evaluating the Effectiveness of Cancer Drug Sensitization In Vitro and In Vivo

Published on: February 6, 2015

8.9K
Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies
13:24

Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies

Published on: April 11, 2016

12.1K

Related Experiment Videos

Last Updated: Nov 16, 2025

A Blood-based Test for the Detection of ROS1 and RET Fusion Transcripts from Circulating Ribonucleic Acid Using Digital Polymerase Chain Reaction
10:35

A Blood-based Test for the Detection of ROS1 and RET Fusion Transcripts from Circulating Ribonucleic Acid Using Digital Polymerase Chain Reaction

Published on: April 5, 2018

10.6K
Evaluating the Effectiveness of Cancer Drug Sensitization In Vitro and In Vivo
09:19

Evaluating the Effectiveness of Cancer Drug Sensitization In Vitro and In Vivo

Published on: February 6, 2015

8.9K
Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies
13:24

Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies

Published on: April 11, 2016

12.1K

Area of Science:

  • Clinical Chemistry
  • Laboratory Medicine
  • Oncology

Background:

  • Timely chemotherapy delivery is crucial for patient outcomes.
  • Laboratory turnaround time (TAT) impacts chemotherapy administration.
  • Optimizing laboratory processes can improve patient care.

Purpose of the Study:

  • To reduce laboratory TAT for key tests supporting chemotherapy.
  • To enhance the efficiency of laboratory testing for oncology patients.

Main Methods:

  • Reconfigured workflows for CBC and CMP testing.
  • Prioritized CMP samples as urgent (STAT).
  • Utilized ABL 800 analyzers for rapid analysis of total bilirubin and creatinine.

Main Results:

  • Median TAT for CBC reduced to 16 minutes.
  • Median TAT for CMP decreased from 74 to 54 minutes.
  • Median TAT for total bilirubin and creatinine reduced to 9 minutes.

Conclusions:

  • Workflow re-engineering significantly decreased overall TAT to under 20 minutes.
  • Optimized laboratory processes facilitate timely chemotherapy administration.
  • Improvements achieved without requiring a satellite laboratory.