Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Effect of Aging on Tissues01:19

The Effect of Aging on Tissues

3.0K
Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
3.0K
Cognitive Development During Adulthood01:30

Cognitive Development During Adulthood

498
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
498
Aging01:26

Aging

422
Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
422
Erikson's Theory on Socioemotional Development during Adulthood01:27

Erikson's Theory on Socioemotional Development during Adulthood

500
Erik Erikson's theory of psychosocial development outlines a series of stages through which individuals progress across the lifespan. Each stage involves a psychosocial conflict that significantly influences personal growth and well-being. Three key stages — intimacy versus isolation, generativity versus stagnation, and integrity versus despair — highlight the developmental challenges faced in adulthood.
Intimacy Versus Isolation in Early Adulthood
Individuals in early...
500
Bone Disorders01:29

Bone Disorders

4.8K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
4.8K
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution01:00

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution

67
Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are...
67

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Supporting NICU Mothers' Breastfeeding Goals During Climate-Related Disasters Using Kumpfer's Resilience Framework and CMIST.

Advances in neonatal care : official journal of the National Association of Neonatal Nurses·2026
Same author

Physical Activity Post-Cardiac Device Implantation in the First 180 Days: Is there a recovery plateau?

Journal of cardiopulmonary rehabilitation and prevention·2026
Same author

President's Pen-Tending the Flame: Caring for Ourselves While Caring for Others.

Research in nursing & health·2025
Same author

Effects of adverse childhood experiences and personal resilience on household emergency preparedness: considerations for disaster planning.

Frontiers in public health·2025
Same author

President's Pen-PhD and DNP Partnerships Across the T0-T4 Research and Translational Cycle.

Research in nursing & health·2025
Same author

President's Pen: Greetings-Dear Colleagues and Friends of the Southern Nursing Research Society!

Research in nursing & health·2025
Same journal

Comparative effects of different interventions on loneliness, social support, and depression in older adults: A network meta-analysis of randomized controlled trials.

Geriatric nursing (New York, N.Y.)·2026
Same journal

Identification of strategies to optimize pain management in people with dementia living in nursing homes using nominal group technique.

Geriatric nursing (New York, N.Y.)·2026
Same journal

Cultural adaptation and validation of the Albanian Barthel index: A reliable tool for assessing functional independence in older adults.

Geriatric nursing (New York, N.Y.)·2026
Same journal

Aetiological diagnosis of cognitive impairment in older adults: The role of geriatric nursing and factors associated with its detection.

Geriatric nursing (New York, N.Y.)·2026
Same journal

Adherence to life's essential 8 and functional disability in older adults: Findings from the ELSI-Brazil study.

Geriatric nursing (New York, N.Y.)·2026
Same journal

From correlation to causation: Evidence-based strategies for promoting IoT adoption among heterogeneous rural elderly populations in China.

Geriatric nursing (New York, N.Y.)·2026
See all related articles

Related Experiment Video

Updated: Nov 16, 2025

Validation of a Psychosocial Intervention on Body Image in Older People: An Experimental Design
07:40

Validation of a Psychosocial Intervention on Body Image in Older People: An Experimental Design

Published on: May 31, 2021

3.6K

Life-space constriction in aging adults.

Tamatha E Arms1, Patricia B Crane2, Charleen McNeill3

  • 1Associate Professor, University of North Carolina Wilmington, 601 S. College Rd., Wilmington, NC 28401, United States.

Geriatric Nursing (New York, N.Y.)
|February 27, 2021
PubMed
Summary
This summary is machine-generated.

Life-space constriction (LSC) is an early sign of declining function and frailty in older adults. Assistive devices were the only significant predictor of frailty in this study.

Keywords:
AdultsAgingFrailtyLife-space constriction

More Related Videos

Surveying Low-Cost Methods to Measure Lifespan and Healthspan in Caenorhabditis elegans
10:08

Surveying Low-Cost Methods to Measure Lifespan and Healthspan in Caenorhabditis elegans

Published on: May 18, 2022

3.7K
Author Spotlight: Investigating the Effects of Mind-Body-Movement Practices on Brain Function
06:17

Author Spotlight: Investigating the Effects of Mind-Body-Movement Practices on Brain Function

Published on: January 26, 2024

2.4K

Related Experiment Videos

Last Updated: Nov 16, 2025

Validation of a Psychosocial Intervention on Body Image in Older People: An Experimental Design
07:40

Validation of a Psychosocial Intervention on Body Image in Older People: An Experimental Design

Published on: May 31, 2021

3.6K
Surveying Low-Cost Methods to Measure Lifespan and Healthspan in Caenorhabditis elegans
10:08

Surveying Low-Cost Methods to Measure Lifespan and Healthspan in Caenorhabditis elegans

Published on: May 18, 2022

3.7K
Author Spotlight: Investigating the Effects of Mind-Body-Movement Practices on Brain Function
06:17

Author Spotlight: Investigating the Effects of Mind-Body-Movement Practices on Brain Function

Published on: January 26, 2024

2.4K

Area of Science:

  • Gerontology
  • Public Health
  • Sociology

Background:

  • Life-space constriction (LSC) is an early indicator of declining function and frailty.
  • Identifying individuals at risk for frailty is crucial for timely intervention.

Purpose of the Study:

  • To examine factors associated with LSC.
  • To investigate the influence of LSC on function and frailty in older adults.

Main Methods:

  • Cross-sectional, descriptive study.
  • Convenience sample of community-dwelling adults aged 55 and older.
  • Analysis of individual, environmental, and social factors.

Main Results:

  • Individual factors explained 22% of the variance in self-reported frailty.
  • LSC explained 34% of the variance in function after controlling for other factors.
  • The number of assistive devices was the sole significant predictor of frailty.

Conclusions:

  • LSC is a significant factor influencing function in older adults.
  • Assistive devices may play a critical role in mitigating frailty.
  • Further research is needed to explore interventions targeting LSC and frailty.