Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Fungal Group Zygomycota01:29

Fungal Group Zygomycota

589
Zygomycota, previously classified as a distinct fungal group, are primarily terrestrial, saprophytic molds that play a crucial role as decomposers. Recent phylogenetic studies have revealed that these fungi are now divided into two major clades — Mucoromycota, which includes many symbiotic species, and Zoopagomycota, which primarily consists of parasitic and pathogenic fungi. These groups exhibit distinct ecological roles and reproductive strategies while sharing key structural and...
589
Overview of Fungi01:29

Overview of Fungi

846
Fungi are a diverse group of eukaryotes more closely related to animals than other eukaryotes. Fungal cell walls comprise chitin, a polysaccharide that provides structural strength, and glucans, which contribute to flexibility and integrity. Other polysaccharides, such as mannans and galactosans, may supplement or replace chitin in some fungi. These adaptations, along with their preference for acidic environments and tolerance for high osmotic pressure, enable fungi to thrive in various...
846
Fungal Phylum Basidiomycota01:26

Fungal Phylum Basidiomycota

541
Basidiomycota is a diverse phylum of fungi that includes ecologically significant decomposers such as white rot fungi, symbionts like mycorrhizal fungi, plant pathogens such as rusts and smuts, and edible species like Agaricus bisporus (the common button mushroom). These fungi play crucial roles in nutrient cycling, symbiotic relationships, and even human health. Their defining feature is the basidium, a microscopic club-shaped structure responsible for producing basidiospores.Fruiting Bodies...
541
Surface Membrane Barriers01:18

Surface Membrane Barriers

2.0K
The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
2.0K
Antimicrobial Proteins01:23

Antimicrobial Proteins

12.3K
Antimicrobial proteins are important components of the immune system. They aid the body in combating pathogens by either killing them directly or hindering their replication processes. Four main types of antimicrobial substances are interferons, the complement system, iron-binding proteins, and antimicrobial proteins.
Interferons
Interferons (IFNs) are proteins produced by lymphocytes, macrophages, and fibroblasts infected with viruses. While IFNs cannot prevent viruses from entering and...
12.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

ReGAIN: A bioinformatics platform for assessing probabilistic co-occurrence between resistance genes in bacterial pathogens.

Bioinformatics (Oxford, England)·2026
Same author

Genome Mining and Characterization of an Uncharacterized Monofunctional Class I Diterpene Synthase From a Marine-Derived Fungus.

Chembiochem : a European journal of chemical biology·2026
Same author

IDBac: an open-access web platform and compendium for the identification of bacteria by MALDI-TOF mass spectrometry.

bioRxiv : the preprint server for biology·2025
Same author

An extremophilic <i>Nocardiopsis</i> strain from Great Salt Lake expands the taxonomic range of mycolic acid biosynthesis.

bioRxiv : the preprint server for biology·2025
Same author

SeqForge: a scalable platform for alignment-based searches, motif detection, and sequence curation across meta/genomic datasets.

BMC bioinformatics·2025
Same author

Arthroscopic outside-in "two-needle suture" technique for anterior horn tears of the lateral meniscus.

Asia-Pacific journal of sports medicine, arthroscopy, rehabilitation and technology·2025

Related Experiment Video

Updated: Nov 16, 2025

Measuring Volatile and Non-volatile Antifungal Activity of Biocontrol Products
06:47

Measuring Volatile and Non-volatile Antifungal Activity of Biocontrol Products

Published on: December 5, 2020

6.9K

Antifungal natural products.

Stephanie C Heard1, Guangwei Wu2, Jaclyn M Winter1

  • 1Department of Medicinal Chemistry, College of Pharmacy, University of Utah, Salt Lake City, UT 84112, USA.

Current Opinion in Biotechnology
|February 28, 2021
PubMed
Summary
This summary is machine-generated.

Natural products offer diverse chemical scaffolds crucial for developing new antifungal drugs. This review highlights existing and potential natural antifungal agents to combat rising drug resistance.

More Related Videos

Quantifying the Antifungal Activity of Peptides Against Candida albicans
06:45

Quantifying the Antifungal Activity of Peptides Against Candida albicans

Published on: January 13, 2023

2.6K
Broth Microdilution In Vitro Screening: An Easy and Fast Method to Detect New Antifungal Compounds
08:54

Broth Microdilution In Vitro Screening: An Easy and Fast Method to Detect New Antifungal Compounds

Published on: February 14, 2018

19.4K

Related Experiment Videos

Last Updated: Nov 16, 2025

Measuring Volatile and Non-volatile Antifungal Activity of Biocontrol Products
06:47

Measuring Volatile and Non-volatile Antifungal Activity of Biocontrol Products

Published on: December 5, 2020

6.9K
Quantifying the Antifungal Activity of Peptides Against Candida albicans
06:45

Quantifying the Antifungal Activity of Peptides Against Candida albicans

Published on: January 13, 2023

2.6K
Broth Microdilution In Vitro Screening: An Easy and Fast Method to Detect New Antifungal Compounds
08:54

Broth Microdilution In Vitro Screening: An Easy and Fast Method to Detect New Antifungal Compounds

Published on: February 14, 2018

19.4K

Area of Science:

  • Natural product chemistry
  • Medicinal chemistry
  • Antimicrobial research

Background:

  • Natural products are vital bioactive molecules with significant pharmaceutical applications.
  • Increasing antifungal resistance necessitates novel therapeutic strategies.
  • Identifying new antifungal agents from natural sources is a priority.

Purpose of the Study:

  • To review clinically important natural product-derived antifungal agents.
  • To identify natural compounds with potential as antifungal drug leads.
  • To emphasize the need for rapid identification and development of novel antifungal therapies.

Main Methods:

  • Literature review of natural products with antifungal activity.
  • Analysis of chemical diversity and mechanisms of action.
  • Assessment of potential for drug development and yield generation.

Main Results:

  • Overview of established natural antifungal agents.
  • Identification of promising natural scaffolds for future drug development.
  • Discussion of challenges in natural product drug discovery.

Conclusions:

  • Natural products are a rich source for novel antifungal drug discovery.
  • Further research is essential to develop these leads into viable therapies.
  • Addressing antifungal resistance requires continued exploration of nature's chemical diversity.