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Updated: Nov 16, 2025

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
Published on: June 21, 2018
Casework applications of probabilistic genotyping methods for DNA mixtures that allow relationships between
Peter J Green1, Julia Mortera2, Lourdes Prieto3
1UTS, Sydney, Australia; University of Bristol, UK.
Abstract:
In both criminal cases and civil cases there is an increasing demand for the analysis of DNA mixtures involving relationships. The goal might be, for example, to identify the contributors to a DNA mixture where the unknown donors may be related, or to infer the relationship between individuals based on a DNA mixture. This paper applies a new approach to modelling and computation for DNA mixtures involving contributors with arbitrarily complex relationships to two real cases from the Spanish Forensic Police.
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